Evidence map›Paper›PMID 31932697›Full record

ArticleScientific reports2020

Noninvasive rapid detection of metabolic adaptation in activated human T lymphocytes by hyperpolarized

Emine Can, Mor Mishkovsky, Hikari A I Yoshihara, Nicolas Kunz, Dominique-Laurent Couturier, Ulf Petrausch, Marie-Agnès Doucey, Arnaud Comment

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Muscle-Derived miR-200a-3p Through Light-Intensity Exercise May Contribute to Improve Memory Dysfunction in Type 2 Diabetic Mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  3. Article
  4. Hyperpolarized [1-European radiology experimental · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. HyperpolarizedNMR in biomedicine · 2021
    Review
  9. Article
  10. Imaging Brain Metabolism Using HyperpolarizedTrends in neurosciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Emine CanLaboratory of Functional and Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne, CH-1015, Lausanne, Switzerland.
Mor MishkovskyLaboratory of Functional and Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne, CH-1015, Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-6816-7462
Hikari A I YoshiharaLaboratory of Functional and Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne, CH-1015, Lausanne, Switzerland.
Nicolas KunzLaboratory of Functional and Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne, CH-1015, Lausanne, Switzerland.
Dominique-Laurent CouturierCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shin Center, Robinson Way, Cambridge, CB2 0RE, United Kingdom.
Ulf PetrauschOnkoZentrum, CH-8038, Zürich, Switzerland.
Marie-Agnès DouceyDepartment of Oncology, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
Arnaud CommentCancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shin Center, Robinson Way, Cambridge, CB2 0RE, United Kingdom. arnaud.comment@ge.com.ORCID http://orcid.org/0000-0002-8484-3448
École Polytechnique Fédérale de Lausanne · CHGeneral Electric (Spain) · ESUniversity of Cambridge · GBUniversity of Lausanne · CH

Funding

Cancer Research UK A29580
6 · The paper itself

Abstract

The metabolic shift induced in human CD4

Indexed as

Adaptation, PhysiologicalGlycolysisLymphocyte ActivationCarbon IsotopesHumansLactic AcidLeukocytes, MononuclearMagnetic Resonance ImagingPyruvate Dehydrogenase ComplexPyruvic AcidT-LymphocytesCarbon IsotopesLactic AcidPyruvate Dehydrogenase ComplexPyruvic Acid

Identifiers

PMID31932697
PMCPMC6957688
OpenAlexW2992892307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.