Evidence map›Paper›PMID 31932659›Full record

ReviewProstate cancer and prostatic diseases2020

"TREXIT 2020": why the time to abandon transrectal prostate biopsy starts now.

Jeremy Grummet, Michael A Gorin, Rick Popert, Tim O'Brien, Alastair D Lamb, Boris Hadaschik, Jan Philipp Radtke, Florian Wagenlehner, Eduard Baco, Caroline M Moore and 13 more

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Prostate cancer and prostatic diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 52 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04685928 nacompletednot on this mapstarted 2021, after this paper: background citation

A Randomized Controlled Trial Comparing Magnetic Resonance Imaging (MRI)-Targeted Biopsy and Extended Transperineal Systematic Biopsy for Detection of Clinically Significant Prostate Cancer: the SMART Trial

TypeinterventionalSponsorChinese University of Hong KongRan2021 to 2024Enrolled403ConditionsProstate CancerArmsMRI and MRI-guided prostate biopsy, TP-arm Systematic biopsy
NCT04797078 nawithdrawnnot on this mapstarted 2023, after this paper: background citation

Prospective Randomized Controlled Study: Free-Hand Transperineal vs. Transrectal Systematic and Image Fusion Targeted Biopsies Under Local Anesthesia Comparing Rate of Significant Cancer Detection and Complication Rates

TypeinterventionalSponsorKarolinska InstitutetRan2023 to 2025Enrolled0ConditionsProstate CancerArmsTransperineal biopsy, Transrectal biopsy
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Trial
  7. Article
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  11. [Efficiency and safety of transperineal prostate biopsy with a single access point].Revista medica del Instituto Mexicano del Seguro Social · 2026
    Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. TRexit is going one step further.Prostate cancer and prostatic diseases · 2024
    Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Jeremy GrummetDepartment of Surgery, Central Clinical School, Monash University, Melbourne, VIC, Australia. jpgrummet@gmail.com.ORCID http://orcid.org/0000-0003-4382-8169
Michael A GorinDepartment of Urology, The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Rick PopertGuy's and St Thomas' Hospital, London, UK.
Tim O'BrienGuy's and St Thomas' Hospital, London, UK.
Alastair D LambOxford University, Oxford, UK.
Boris HadaschikEssen University Hospital, Essen, Germany.
Jan Philipp RadtkeEssen University Hospital, Essen, Germany.
Florian WagenlehnerJustus-Liebig University, Gießen, Germany.
Eduard BacoOslo University Hospital, Oslo, Norway.
Caroline M MooreUniversity College London, London, UK.
Mark EmbertonUniversity College London, London, UK.ORCID http://orcid.org/0000-0003-4230-0338
Arvin K GeorgeUniversity of Michigan, Ann Arbor, MI, USA.
John W DavisMD Anderson Cancer Center, Houston, TX, USA.
Richard J SzaboSouthern California Kaiser Permanente, Los Angeles, CA, USA.
Roger BuckleyNorth York General Hospital, North York, ON, Canada.
Andrew LoblawOdette Cancer Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.ORCID http://orcid.org/0000-0002-4883-1781
Matthew AllawayUrology Associates, Baltimore, MD, USA.
Christof KastnerAddenbrookes Hospital, Cambridge University, Cambridge, UK.
Erik BriersEuropean Cancer Patient Coalition, Brussels, Belgium.
Peter L RoyceDepartment of Surgery, Central Clinical School, Monash University, Melbourne, VIC, Australia.
Mark FrydenbergMonash University, Clayton, VIC, Australia.
Declan G MurphyPeter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC, Australia.
Henry H WooSydney Adventist Hospital, University of Sydney, Sydney, NSW, Australia.

Funding

Cancer Research UK 25812
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiopsyHumansMaleProstateProstatic NeoplasmsRectum

Identifiers

PMID31932659
PMCPMC7027966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.