Evidence map›Paper›PMID 31932647›Full record

ArticleNature communications2020

Annexin-V stabilizes membrane defects by inducing lipid phase transition.

Yi-Chih Lin, Christophe Chipot, Simon Scheuring

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 110 citations in OpenAlex.

  1. Design of Fluorescent Membrane Scaffold Proteins for Nanodiscs.bioRxiv : the preprint server for biology · 2026
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Yi-Chih LinDepartment of Anesthesiology, Weill Cornell Medicine, 1300 York Avenue, New York, NY, 10065, USA.ORCID http://orcid.org/0000-0002-6498-215X
Christophe ChipotUMR 7019, Université de Lorraine, Laboratoire International Associé CNRS and University of Illinois at Urbana-Champaign, Vandoeuvre-lès-Nancy, F-54500, France.ORCID http://orcid.org/0000-0002-9122-1698
Simon ScheuringDepartment of Anesthesiology, Weill Cornell Medicine, 1300 York Avenue, New York, NY, 10065, USA. sis2019@med.cornell.edu.ORCID http://orcid.org/0000-0003-3534-069X
Cornell University · USCentre National de la Recherche Scientifique · FR

Funding

Enabling physical stimuli in the study of structural dynamics: The sensory ion channelsDP1AT010874 · NCCIH · WEILL MEDICAL COLL OF CORNELL UNIV · PI SCHEURING, SIMON · 2019 to 2023
$5.9M
NCCIH NIH HHS DP1 AT010874
6 · The paper itself

Abstract

Annexins are abundant cytoplasmic proteins, which bind to membranes that expose negatively charged phospholipids in a Ca

Indexed as

Annexin A5CalciumFluorescence Recovery After PhotobleachingLipid BilayersMembrane FusionMicroscopy, Atomic ForceMicroscopy, ConfocalMolecular Dynamics SimulationPhase TransitionPhosphatidylserinesProtein AggregatesAnnexin A5CalciumLipid BilayersPhosphatidylserinesProtein Aggregates

Identifiers

PMID31932647
PMCPMC6957514
OpenAlexW3000511937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.