ArticleScientific reports2020
Contrasting seasonal patterns of telomere dynamics in response to environmental conditions in the ectothermic sand lizard, Lacerta agilis.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Pervasive sublethal impacts of heat exposure revealed by telomere dynamics.Proceedings. Biological sciences · 2026Article
- Telomere Length Is Determined by Intrinsic Factors and Is Shortened During Drought Years inEcology and evolution · 2026Article
- Is Telomere Length Optimized in Hatchling Sand Lizards?Evolution & development · 2025Article
- Chemical signal diversity in male sand lizards (Lacerta agilis) along an urbanization gradient.Scientific reports · 2025Article
- Sex and early-life conditions shape telomere dynamics in an ectotherm.The Journal of experimental biology · 2024Article
- Article
- Habitat restoration weakens negative environmental effects on telomere dynamics.Molecular ecology · 2022Article
- Inbreeding effects on telomeres in hatchling sand lizards (Lacerta agilis): An optimal family affair?Molecular ecology · 2022Article
- Lizards from warm and declining populations are born with extremely short telomeres.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Causes and consequences of variation in early-life telomere length in a bird metapopulation.Ecology and evolution · 2022Article
- Hot and dry conditions predict shorter nestling telomeres in an endangered songbird: Implications for population persistence.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Individual telomere dynamics and their links to life history in a viviparous lizard.Proceedings. Biological sciences · 2021Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Telomeres, the protective, terminal parts of the chromosomes erode during cell division and as a result of oxidative damage by reactive oxygen species (ROS). Ectotherms rely on the ambient temperature for maintaining temperature-dependent metabolic rate, regulated through behavioural thermoregulation. Their temperature-dependant metabolism, hence also the ROS production, is indirectly regulated through thermoregulation. Consequently, a potential causal chain affecting telomere length and attrition is: temperature (in particular, its deviation from a species-specific optimum) - metabolism - ROS production - anti-oxidation - telomere erosion. We measured telomere length in sand lizards (Lacerta agilis) using qPCR on blood samples from 1998-2006. Effects of climatological parameters (mean temperature and average sunshine hours) in the summer and winter preceding telomere sampling were used as predictors of telomere length in mixed model analysis. During the lizards' active period (summer), there was a largely negative effect of mean temperature and sun on telomere length, whereas a combined measure of age and size (head length) was positively related to telomere length. During the inactive period of lizards (winter), the results were largely the opposite with a positive relationship between temperature and sunshine hours and telomere length. In all four cases, thermal and age effects on telomere length appeared to be non-linear in the two sexes and seasons, with complex response surface effects on telomere length from combined age and thermal effects.
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