Evidence map›Paper›PMID 31932602›Full record

ArticleScientific reports2020

Three-dimensional reconstruction of the feeding apparatus of the tick Ixodes ricinus (Acari: Ixodidae): a new insight into the mechanism of blood-feeding.

Marie Vancová, Tomáš Bílý, Ladislav Šimo, Jan Touš, Petr Horodyský, Daniel Růžek, Adam Novobilský, Jiří Salát, Martin Strnad, Daniel E Sonenshine and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 33 citations in OpenAlex.

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  10. What do we know about the microbiome ofFrontiers in cellular and infection microbiology · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 3 countries.

Marie VancováInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, Branišovská 31, CZ-37005, České Budějovice, Czech Republic. vancova@paru.cas.cz.
Tomáš BílýInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, Branišovská 31, CZ-37005, České Budějovice, Czech Republic.
Ladislav ŠimoUMR BIPAR, INRAE, Ecole Nationale Vétérinaire d'Alfort, ANSES, Université Paris-Est, Maisons-Alfort, France.
Jan ToušCrytur, spol. s r.o., Na Lukách 2283, CZ-51101, Turnov, Czech Republic.
Petr HorodyskýCrytur, spol. s r.o., Na Lukách 2283, CZ-51101, Turnov, Czech Republic.
Daniel RůžekInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, Branišovská 31, CZ-37005, České Budějovice, Czech Republic.
Adam NovobilskýVeterinary Research Institute, Hudcova 296/70, CZ-621 00, Brno, Czech Republic.
Jiří SalátVeterinary Research Institute, Hudcova 296/70, CZ-621 00, Brno, Czech Republic.
Martin StrnadInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, Branišovská 31, CZ-37005, České Budějovice, Czech Republic.
Daniel E SonenshineLaboratory for Malaria and Vector Research, NIAID, National Institutes of Health, Rockville, Maryland, USA.
Libor GrubhofferInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, Branišovská 31, CZ-37005, České Budějovice, Czech Republic.
Jana NebesářováInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, Branišovská 31, CZ-37005, České Budějovice, Czech Republic.
Czech Academy of Sciences, Biology Centre · CZCrytur (Czechia) · CZVeterinary Research Institute · CZAgence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail · FRCharles University · CZInstitute of Parasitology · CZNational Institutes of Health · USUniversity of South Bohemia in České Budějovice · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The different components of the mouthparts of hard ticks (Ixodidae) enable these parasites to penetrate host skin, secrete saliva, embed, and suck blood. Moreover, the tick's mouthparts represent a key route for saliva-assisted pathogen transmission as well as pathogen acquisition from blood meal during the tick feeding process. Much has been learned about the basic anatomy of the tick's mouthparts and in the broad outlines of how they function in previous studies. However, the precise mechanics of these functions are little understood. Here, we propose for the first time an animated model of the orchestration of the tick mouthparts and associated structures during blood meal acquisition and salivation. These two actions are known to alternate during tick engorgement. Specifically, our attention has been paid to the mechanism underlining the blood meal uptake into the pharynx through the mouth  and how ticks prevent mixing the uptaken blood with secreted saliva. We animated function of muscles attached to the salivarium and their possible opening /closing of the salivarium, with a plausible explanation of the movement of saliva within the salivarium and massive outpouring of saliva.

Indexed as

Feeding BehaviorSalivationAnimalsFemaleImaging, Three-DimensionalIxodesMiceMicroscopy, Electron, ScanningMouthNymphTick Infestations

Identifiers

PMID31932602
PMCPMC6957509
OpenAlexW3000140571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.