ArticleThe Journal of veterinary medical science2020
Evaluation of the caudal vena cava diameter to abdominal aortic diameter ratio and the caudal vena cava respiratory collapsibility for predicting fluid responsiveness in a heterogeneous population of hospitalized conscious dogs.
Article in The Journal of veterinary medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Diagnostic Significance of Renal Artery Resistive Index (RRI), Caudal Vena Cava Diameter (CVC), and Aorta (Ao) in Dogs with Hypovolemia.Veterinary sciences · 2026Article
- Point-of-care-ultrasound measurements of cardiovascular indices across awake, sedated, anesthetized, and recovered states in dogs.Frontiers in veterinary science · 2026Article
- Computed tomographic assessment of abdominal aortic diameter is not associated with systemic hypertension in dogs: A preliminary study.Open veterinary journal · 2025Article
- Ultrasonographic Assessment of Caudal Vena Cava Collapsibility Index, Caudal Vena Cava-to-Aorta, and Femoral Vein-to-Artery Ratios in Healthy Sedated Adult Horses.Animals : an open access journal from MDPI · 2025Article
- Point of care ultrasound measurement of paralumbar caudal vena cava diameter and caudal vena cava to aortic ratio in hypovolemic dogs.Frontiers in veterinary science · 2024Article
- Evaluation of caudal vena cava size using computed tomography in dogs under general anesthesia.The Journal of veterinary medical science · 2022Article
- Development and comparison of an esophageal Doppler monitoring-based treatment algorithm with a heart rate and blood pressure-based treatment algorithm for goal-directed fluid therapy in anesthetized dogs: A pilot study.Frontiers in veterinary science · 2022Article
- Assessment of Volume Status and Fluid Responsiveness in Small Animals.Frontiers in veterinary science · 2021Review
- Clinical Application of the Fluid Challenge Approach in Goal-Directed Fluid Therapy: What Can We Learn From Human Studies?Frontiers in veterinary science · 2021Review
- Fluid Overload.Frontiers in veterinary science · 2021Review
- Intravenous Bolus Fluid Therapy Versus No Fluid Therapy Prior to Pericardiocentesis in Dogs: A Randomized Controlled Trial in 30 Dogs.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fluid responsiveness, defined as the response of stroke volume to fluid loading, is a tool to individualize fluid administration in order to avoid the deleterious effects of hypovolemia or hypervolemia in hospitalized patients. To evaluate the accuracy of two ultrasound indices, the caudal vena cava to abdominal aorta ratio (CVC/Ao) and the respiratory collapsibility of the caudal vena cava (cCVC), as independent predictors of fluid responsiveness in a heterogeneous population of spontaneously breathing, conscious, hospitalized dogs. A prospective, multicenter, observational, cross-sectional study was designed in twenty-five dogs. The accuracy of CVC/Ao and cCVC in predicting fluid responsiveness was evaluated by the area under the receiver operating characteristic curve (AUROC) in a group of hospitalized dogs after receiving a mini-fluid bolus of 4 ml/kg of Hartmann's solution. Dogs with an increased aortic velocity time integral >15% were classified as fluid responders. Twenty-two dogs were finally included. Ten were classified as responders and 12 as non-responders. The AUROC curves were 0.88 for the CVC/Ao ratio (95% confidence interval, CI, 0.67-0.98; P=0.0001) and 0.54 for cCVC (95% CI 0.32-0.75; P=0.75). The CVC/Ao threshold optimized for best sensitivity (SE) and specificity (SP) values was 0.83 (SE 100%; SP 75%). In spontaneously breathing hospitalized dogs, the CVC/Ao measurement predicted stroke volume increase after a fluid bolus, while the respiratory variations in the cCVC did not discriminate between fluid responders and non-responders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.