Evidence map›Paper›PMID 31932483›Full record

ArticleMolecular and cellular biology2020

A Redox-Sensitive Thiol in Wis1 Modulates the Fission Yeast Mitogen-Activated Protein Kinase Response to H

Johanna J Sjölander, Agata Tarczykowska, Cecilia Picazo, Itziar Cossio, Itedale Namro Redwan, Chunxia Gao, Carlos Solano, Michel B Toledano, Morten Grøtli, Mikael Molin and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and cellular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Oxidative stress response pathways in fungi.Cellular and molecular life sciences : CMLS · 2022
    Review
  3. Extension of chronological lifespan in Schizosaccharomyces pombe.Genes to cells : devoted to molecular & cellular mechanisms · 2021
    Review
  4. Article
  5. Looking Back at the Early Stages of Redox Biology.Antioxidants (Basel, Switzerland) · 2020
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Johanna J SjölanderUniversity of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.
Agata TarczykowskaUniversity of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.
Cecilia PicazoUniversity of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.
Itziar CossioUniversity of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.
Itedale Namro RedwanUniversity of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.
Chunxia GaoUniversity of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.
Carlos SolanoUniversity of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.
Michel B ToledanoOxidative Stress and Cancer Laboratory, Integrative Biology and Molecular Genetics Unit, CEA Saclay, Gif-sur-Yvette, France.
Morten GrøtliUniversity of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden.
Mikael MolinUniversity of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden mikael.molin@chalmers.se per.sunnerhagen@cmb.gu.se.
Per SunnerhagenUniversity of Gothenburg, Department of Chemistry and Molecular Biology, Gothenburg, Sweden mikael.molin@chalmers.se per.sunnerhagen@cmb.gu.se.ORCID 0000-0002-0967-8729
University of Gothenburg · SEChalmers University of Technology · SECommissariat à l'Énergie Atomique et aux Énergies Alternatives · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidation of a highly conserved cysteine (Cys) residue located in the kinase activation loop of mitogen-activated protein kinase kinases (MAPKK) inactivates mammalian MKK6. This residue is conserved in the fission yeast

Indexed as

CysteineGene Expression Regulation, FungalHydrogen PeroxideMitogen-Activated Protein Kinase KinasesMitogen-Activated Protein KinasesOxidation-ReductionProtein Kinase InhibitorsSchizosaccharomycesSchizosaccharomyces pombe ProteinsSequence AlignmentCysteineHydrogen PeroxideMitogen-Activated Protein Kinase KinasesMitogen-Activated Protein KinasesProtein Kinase InhibitorsSchizosaccharomyces pombe Proteinssty1 protein, S pombewis1 protein, S pombecysteine oxidationSchizosaccharomyces pombestress signalingSty1

Identifiers

PMID31932483
PMCPMC7076255
OpenAlexW3000058993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.