Evidence map›Paper›PMID 31932480›Full record

ArticleMolecular and cellular biology2020

An F-Box Protein, Mdm30, Interacts with TREX Subunit Sub2 To Regulate Cellular Abundance Cotranscriptionally in Orchestrating mRNA Export Independently of Splicing and Mitochondrial Function.

Jannatul Ferdoush, Rwik Sen, Geetha Durairaj, Priyanka Barman, Amala Kaja, Shalini Guha, Sukesh R Bhaumik

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jannatul Ferdoush *Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA.
Rwik Sen *Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA.
Geetha Durairaj *Department of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA.
Priyanka BarmanDepartment of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA.
Amala KajaDepartment of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA.
Shalini GuhaDepartment of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA.
Sukesh R BhaumikDepartment of Biochemistry and Molecular Biology, Southern Illinois University School of Medicine, Carbondale, Illinois, USA sbhaumik@siumed.edu.
Southern Illinois University School of Medicine · US

Funding

Ubiquitin-proteasome system regulation of a transcriptional co-activator, SAGA, and associated functionsR15GM088798 · NIGMS · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI BHAUMIK, SUKESH R. · 2009 to 2018
$997k
NIGMS NIH HHS R15 GM088798
6 · The paper itself

Abstract

Although an F-box protein, Mdm30, is found to regulate ubiquitylation of the Sub2 component of TREX (

Indexed as

Active Transport, Cell NucleusAdenosine TriphosphatasesF-Box ProteinsGTP PhosphohydrolasesMembrane ProteinsMitochondriaMitochondrial DynamicsMitochondrial ProteinsProteasome Endopeptidase ComplexRNA, MessengerRNA SplicingRNA TransportSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription, GeneticUbiquitinationAdenosine TriphosphatasesF-Box ProteinsFZO1 protein, S cerevisiaeGTP PhosphohydrolasesMdm30 protein, S cerevisiaeMembrane ProteinsMitochondrial ProteinsProteasome Endopeptidase ComplexRNA-dependent ATPaseRNA, MessengerSaccharomyces cerevisiae Proteinsgene expressionMdm30mRNA exportmRNA splicingSub2transcription

Identifiers

PMID31932480
PMCPMC7076257
OpenAlexW2999822229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.