Evidence map›Paper›PMID 31932451›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Polymeric sheet actuators with programmable bioinstructivity.

Zijun Deng, Weiwei Wang, Xun Xu, Oliver E C Gould, Karl Kratz, Nan Ma, Andreas Lendlein

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Carboxyl-Alkyl Functionalized Conjugated Polyelectrolytes for High Performance Organic Electrochemical Transistors.Chemistry of materials : a publication of the American Chemical Society · 2023
    Article
  5. CaCellular signalling · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zijun DengInstitute of Biomaterial Science, Helmholtz-Zentrum Geesthacht, 14513 Teltow, Germany.
Weiwei WangInstitute of Biomaterial Science, Helmholtz-Zentrum Geesthacht, 14513 Teltow, Germany.
Xun XuInstitute of Biomaterial Science, Helmholtz-Zentrum Geesthacht, 14513 Teltow, Germany.
Oliver E C GouldInstitute of Biomaterial Science, Helmholtz-Zentrum Geesthacht, 14513 Teltow, Germany.
Karl KratzInstitute of Biomaterial Science, Helmholtz-Zentrum Geesthacht, 14513 Teltow, Germany.
Nan MaInstitute of Biomaterial Science, Helmholtz-Zentrum Geesthacht, 14513 Teltow, Germany; Nan.Ma@hzg.de andreas.lendlein@hzg.de.
Andreas LendleinInstitute of Biomaterial Science, Helmholtz-Zentrum Geesthacht, 14513 Teltow, Germany; Nan.Ma@hzg.de andreas.lendlein@hzg.de.
Helmholtz-Zentrum Hereon · DEFreie Universität Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cells are capable of sensing and processing environmental inputs, converting this information to output a specific cell lineage through signaling cascades. Despite the combinatorial nature of mechanical, thermal, and biochemical signals, these stimuli have typically been decoupled and applied independently, requiring continuous regulation by controlling units. We employ a programmable polymer actuator sheet to autonomously synchronize thermal and mechanical signals applied to mesenchymal stem cells (MSCs). Using a grid on its underside, the shape change of polymer sheet, as well as cell morphology, calcium (Ca

Indexed as

OsteogenesisStress, MechanicalTemperatureAdipose TissueCalciumCell DifferentiationCell LineageCells, CulturedHumansMechanotransduction, CellularPolymersStem CellsTissue EngineeringCalciumPolymerscalcium influxHDAC1mesenchymal stem cellsreversible shape-memory actuatorRUNX2

Identifiers

PMID31932451
PMCPMC6995006
OpenAlexW2999713776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.