Evidence map›Paper›PMID 31932440›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Membrane molecular crowding enhances MreB polymerization to shape synthetic cells from spheres to rods.

David Garenne, Albert Libchaber, Vincent Noireaux

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Membrane-Associated Biomolecules for Synthetic Cell Signalling.Chembiochem : a European journal of chemical biology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Macromolecular crowding: Sensing without a sensor.Current opinion in cell biology · 2023
    Review
  13. Article
  14. Article
  15. Water Stress-Driven Changes in Bacterial Cell Surface Properties.Applied and environmental microbiology · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

David GarenneSchool of Physics and Astronomy, University of Minnesota, Minneapolis, MN 55455.
Albert LibchaberCenter for Studies in Physics and Biology, The Rockefeller University, New York, NY 10021 libchbr@rockefeller.edu noireaux@umn.edu.
Vincent NoireauxSchool of Physics and Astronomy, University of Minnesota, Minneapolis, MN 55455; libchbr@rockefeller.edu noireaux@umn.edu.ORCID 0000-0002-5213-273X
University of Minnesota · USRockefeller University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Executing gene circuits by cell-free transcription-translation into cell-sized compartments, such as liposomes, is one of the major bottom-up approaches to building minimal cells. The dynamic synthesis and proper self-assembly of macromolecular structures inside liposomes, the cytoskeleton in particular, stands as a central limitation to the development of cell analogs genetically programmed. In this work, we express the

Indexed as

Cell ShapeArtificial CellsCell MembraneCytoskeletonEscherichia coliEscherichia coli ProteinsLiposomesPolymerizationProtein BiosynthesisProtein ConformationEscherichia coli ProteinsLiposomesMreB protein, E colicell-free transcription−translationmolecular crowdingMreB cytoskeletonsymmetry breakingsynthetic cell

Identifiers

PMID31932440
PMCPMC6994999
OpenAlexW3000596895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.