Evidence map›Paper›PMID 31932361›Full record

ArticlePediatrics2020

Mandatory Vaccination in Europe.

Olivia M Vaz, Mallory K Ellingson, Paul Weiss, Samuel M Jenness, Azucena Bardají, Robert A Bednarczyk, Saad B Omer

Open access · greenAbstract read
In one paragraph

Article in Pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 108 citations in OpenAlex.

  1. Pooled it
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  14. Reducing Barriers to COVID-19 Vaccination Uptake: Community Ideas from Urban and Rural Kenya.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Olivia M VazDepartments of Epidemiology and.
Mallory K EllingsonHubert Department of Global Health, Rollins School of Public Health, mallory.ellingson@yale.edu.
Paul WeissBiostatistics and Bioinformatics.
Samuel M JennessDepartments of Epidemiology and.
Azucena BardajíHospital Clínic, Barcelona Institute for Global Health, Universitat de Barcelona, Barcelona, Spain.
Robert A BednarczykDepartments of Epidemiology and.
Saad B OmerDepartments of Epidemiology and.
Barcelona Institute for Global Health · ESEmory and Henry College · USEmory University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
EpiModel 2.0: Integrated Network Models for HIV/STI Prevention ScienceR01AI138783 · NIAID · EMORY UNIVERSITY · PI JENNESS, SAMUEL · 2018 to 2021
$3.0M
NCATS NIH HHS UL1 TR001863NIAID NIH HHS R01 AI138783
6 · The paper itself

Abstract

backgroundMandatory vaccination has been effective in maintaining high vaccination coverage in countries such as the United States. However, there are no peer-reviewed analyses of the association between mandates and both coverage and subsequent incidence of vaccine-preventable disease in Europe.

methodsUsing data from the European Centre for Disease Prevention and Control and the World Health Organization, we evaluated the relationship between country-level mandatory vaccination policies and (1) measles and pertussis vaccine coverage and (2) the annual incidence of these diseases in 29 European countries. Multivariate negative binomial and linear regression models were used to quantify these associations.

resultsMandatory vaccination was associated with a 3.71 (95% confidence interval [CI]: 1.68 to 5.74) percentage point higher prevalence of measles vaccination and a 2.14 (95% CI: 0.13 to 4.15) percentage point higher prevalence of pertussis vaccination when compared with countries that did not have mandatory vaccination. Mandatory vaccination was only associated with decreased measles incidence for countries without nonmedical exemptions (adjusted incidence rate ratio = 0.14; 95% CI: 0.05 to 0.36). We did not find a significant association between mandatory vaccination and pertussis incidence.

conclusionsMandatory vaccination and the magnitude of fines were associated with higher vaccination coverage. Moreover, mandatory vaccination was associated with lower measles incidence for countries with mandatory vaccination without nonmedical exemptions. These findings can inform legislative policies aimed at increasing vaccination coverage.

Indexed as

Confidence IntervalsEuropeHumansIncidenceMandatory ProgramsMeaslesMeasles VaccinePertussis VaccineVaccination CoverageWhooping CoughMeasles VaccinePertussis Vaccine

Identifiers

PMID31932361
PMCPMC7011108
OpenAlexW3000372134

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.