Evidence map›Paper›PMID 31932358›Full record

ArticleSexually transmitted infections2020

Prevalence and incidence of

Carolyn P Smullin, Hunter Green, Remco Peters, Dorothy Nyemba, Yamkela Qayiya, Landon Myer, Jeffrey Klausner, Dvora Joseph Davey

Open access · greenAbstract read
In one paragraph

Article in Sexually transmitted infections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Adverse pregnancy and perinatal outcomes associated withSexually transmitted infections · 2022
    Pooled it
  2. Article
  3. medRxiv : the preprint server for health sciences · 2026
    Article
  4. Prevalence ofInfectious disease reports · 2026
    Article
  5. Article
  6. Prevalence and epidemiology ofFrontiers in public health · 2025
    Article
  7. Molecular Exploration ofPathogens (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Prevalence of Mycoplasma genitalium infection and macrolide resistance in pregnant women receiving prenatal care.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2023
    Article
  12. Significant Associations betweenInfectious diseases in obstetrics and gynecology · 2022
    Article
  13. Lack of macrolide resistance inSexually transmitted infections · 2021
    Article
  14. Pathogens (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Sexually transmitted infections in pregnant women from sub-Saharan Africa.Southern African journal of infectious diseases · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Carolyn P SmullinDavid Geffen School of Medicine, Los Angeles, California, USA csmullin@mednet.ucla.edu.ORCID 0000-0002-0794-5790
Hunter GreenEpidemiology, University of California Los Angeles Jonathan and Karin Fielding School of Public Health, Los Angeles, California, USA.
Remco PetersPublic Health, University of the Witwatersrand, Johannesburg-Braamfontein, Gauteng, South Africa.
Dorothy NyembaEpidemiology and Biostatistics, University of Cape Town School of Public Health and Family Medicine, Observatory, Western Cape, South Africa.
Yamkela QayiyaEpidemiology and Biostatistics, University of Cape Town School of Public Health and Family Medicine, Observatory, Western Cape, South Africa.
Landon MyerEpidemiology and Biostatistics, University of Cape Town School of Public Health and Family Medicine, Observatory, Western Cape, South Africa.
Jeffrey KlausnerDavid Geffen School of Medicine, Los Angeles, California, USA.
Dvora Joseph DaveyEpidemiology, University of California Los Angeles Jonathan and Karin Fielding School of Public Health, Los Angeles, California, USA.
University of Cape Town · ZAUniversity of California, Los Angeles · USUniversity of the Witwatersrand · ZA

Funding

Clinical Study of STI Screening to Prevent Adverse Birth and Newborn OutcomesR01AI149339 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KLAUSNER, JEFFREY DAVID, MEDINA-MARINO, ANDREW · 2020 to 2024
$4.3M
Evaluating the PrEP cascade in HIV-negative pregnant and breastfeeding women in South Africa (PrEP-PP)R01MH116771 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOSEPH DAVEY, DVORA LEAH, MYER, BENJAMIN LANDON · 2018 to 2022
$2.5M
Evaluation of pre-exposure prophylaxis cascade in pregnant and breastfeeding women in Cape Town, South AfricaK01TW011187 · FIC · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOSEPH DAVEY, DVORA LEAH · 2018 to 2022
$698k
FIC NIH HHS K01 TW011187NIAID NIH HHS R01 AI149339NIMH NIH HHS R01 MH116771
6 · The paper itself

Abstract

objective

methodsWe conducted a cohort study of 197 women ≥18 years receiving antenatal care in South Africa from November 2017 to February 2019. We over-recruited HIV-infected pregnant women to compare MG by HIV infection status. Self-collected vaginal swabs, performed at the first antenatal visit, third trimester and within 1 week post partum, were tested for MG using the Aptima assay (Hologic, USA). We report on the prevalence and incidence of MG and used multivariable logistic regression to describe correlates of MG and adverse pregnancy and birth outcomes (preterm delivery, miscarriage and vertical HIV transmission), adjusting for maternal age and HIV infection status.

resultsAt first antenatal visit, the median age was 29 years (IQR=24-34) and the gestational age was 19 weeks (IQR=14-23); 47% of women enrolled in the study were HIV-infected. MG prevalence was 24% (95% CI 16% to 34%, n=22) in HIV-infected and 12% (95% CI 6.8% to 20%, n=13) in HIV-uninfected pregnant women. MG incidence during pregnancy and early post partum was 4.7 infections per 100 woman-years (95% CI 1.2 to 12.9) or 3.9 per 1000 woman-months (95% CI 1.0 to 10.7). Adjusting for maternal age, HIV-infected women had over three times the odds of being infected with MG (adjusted OR=3.09, 95% CI 1.36 to 7.06).

conclusionWe found a high prevalence and incidence of MG in pregnant women. Younger maternal age and HIV infection were associated with MG infection in pregnancy. Further research into birth outcomes of women infected with MG, including vertical transmission of HIV infection, is needed.

Indexed as

Mycoplasma genitaliumAdultCohort StudiesFemaleHIV InfectionsHumansIncidenceMycoplasma InfectionsPregnancyPregnancy Complications, InfectiousPregnancy OutcomePregnant PeoplePrenatal CarePrevalenceSouth AfricaHIVM genitaliumpregnancy

Identifiers

PMID31932358
PMCPMC7354884
OpenAlexW2999408493

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.