Evidence map›Paper›PMID 31931955›Full record

ReviewDeutsches Arzteblatt international2019

Reducing the Risk of Preterm Birth by Ambulatory Risk Factor Management.

Richard Berger, Werner Rath, Harald Abele, Yves Garnier, Ruben-J Kuon, Holger Maul

Abstract readReview
In one paragraph

Review in Deutsches Arzteblatt international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

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  17. Preterm Birth Rate in Germany- No Numbers Exist for This.Deutsches Arzteblatt international · 2020
    Article
  18. Notable Shortcomings.Deutsches Arzteblatt international · 2020
    Article
  19. In Reply.Deutsches Arzteblatt international · 2020
    Article
  20. Hematologic or Vascular Risks as Possible Causes.Deutsches Arzteblatt international · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Richard BergerMarienhaus Klinikum St. Elisabeth, Department of Gynecology and Obstetrics, Neuwied; University Medical Center Schleswig-Holstein, Campus Kiel; Tübingen University Hospital, Center for Women's Health, Tübingen; Klinikum Osnabrück GmbH, Department of Gynecology and Obstetrics, Osnabrück; Heidelberg University Hospital, Department of Gynecology and Obstetrics, Heidelberg; Asklepios Kliniken Barmbek, Wandsbek und Nord-Heidberg, Department of Gynecology and Obstetrics, Hamburg.
Werner Rath
Harald Abele
Yves Garnier
Ruben-J Kuon
Holger Maul
Klinikum Osnabrück · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe preterm birth rate in Germany has remained unchanged at 8-9% since 2009. Preterm birth is the most common cause of neonatal morbidity and mortality. In the absence of a causal treatment, it is important to lower the risk of preterm birth by preventive measures in prenatal outpatient care.

methodsThis review is based on pertinent publications from the years 2000-2019 that were retrieved by a selective search in PubMed.

resultsThe clinical risk factors for preterm birth-known mainly from retrospective cohort studies-include previous preterm birth (adjusted odds ratio [aOR]: 3.6), multiple pregnancy (relative risk [RR]: 7.7), nicotine consumption (aOR: 1.7), and a short uterine cervix, i.e., <25 mm in the second trimester (aOR: 6.9). In women with a short cervix, vaginally administered progesterone significantly lowers the preterm birth rate (22.5% vs. 14.1% for birth before 33 weeks of gestation, RR: 0.62; 95% confidence interval [0.47; 0.81]). Nicotine abstinence is associated with a lower pre- term birth rate as well (aOR: 0.91; [0.88; 0,.94]), while working more than 40 hours per week (aOR: 1.25; [1,.01; 1,.54]) and heavy lifting during pregnancy (hazard ratio [HR]: 1.43; [1.13; 1.80]) are associated with a higher preterm birth rate. Avoidance of physical exertion, or bed rest, in the face of impending preterm birth does not lower the preterm birth rate, but it does increase the risk of complications, such as thromboembolism.

conclusionThe meticulous assessment and elimination of treatable risk factors at the outset of ambulatory prenatal care can help lower the preterm birth rate. Further velopment of causally directed treat- ments (e.g., changes of relevant environmental and epigenetic factors).

Indexed as

Ambulatory CarePrenatal CareFemaleGermanyHumansPregnancyPremature BirthRetrospective StudiesRisk Factors

Identifiers

PMID31931955
PMCPMC6970314
OpenAlexW3006136421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.