Evidence map›Paper›PMID 31931844›Full record

Observational studyCritical care (London, England)2020

Should the ultrasound probe replace your stethoscope? A SICS-I sub-study comparing lung ultrasound and pulmonary auscultation in the critically ill.

Eline G M Cox, Geert Koster, Aidan Baron, Thomas Kaufmann, Ruben J Eck, T Corien Veenstra, Bart Hiemstra, Adrian Wong, Thomas C Kwee, Jaap E Tulleken and 4 more

Registry-linked trialOpen access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Critical care (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02912624 (Combining Conventional With Advanced Hemodynamic Parameters for Predicting the Outcome of Critically Ill Patients), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02912624 completednot on this map

Combining Conventional With Advanced Hemodynamic Parameters for Predicting the Outcome of Critically Ill Patients: a Pilot for a Registry

Typeobservational_patient_registrySponsorUniversity Medical Center GroningenRan2015 to 2017Enrolled1,090ConditionsCritical Illness, Acute Disease, Shock
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Article
  3. [Research on portable airway impedance monitoring device based on expiratory oscillation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Automated 3D thorax model generation using handheld video-footage.International journal of computer assisted radiology and surgery · 2022
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. [German recommendations on lung and thoracic ultrasonography in patients with COVID-19].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Eline G M CoxDepartment of Critical Care, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands. e.g.m.cox@umcg.nl.ORCID 0000-0003-0821-7362
Geert KosterDepartment of Critical Care, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
Aidan BaronEmergency, Cardiovascular, and Critical Care Research Group, Centre for Health and Social Care Research, Kingston University and St George's University, London, UK.
Thomas KaufmannDepartment of Anesthesiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Ruben J EckDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
T Corien VeenstraDepartment of Critical Care, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
Bart HiemstraDepartment of Anesthesiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Adrian WongDepartment of Anaesthesiology and Intensive Care, Royal Surrey County Hospital, Guildford, UK.
Thomas C KweeDepartment of Radiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Jaap E TullekenDepartment of Critical Care, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
Frederik KeusDepartment of Critical Care, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
Renske WiersemaDepartment of Critical Care, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
Iwan C C van der HorstDepartment of Intensive Care, Maastricht University Medical Center+, Maastricht University, Maastricht, The Netherlands.
SICS Study Group
University Medical Center Groningen · NLMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn critically ill patients, auscultation might be challenging as dorsal lung fields are difficult to reach in supine-positioned patients, and the environment is often noisy. In recent years, clinicians have started to consider lung ultrasound as a useful diagnostic tool for a variety of pulmonary pathologies, including pulmonary edema. The aim of this study was to compare lung ultrasound and pulmonary auscultation for detecting pulmonary edema in critically ill patients.

methodsThis study was a planned sub-study of the Simple Intensive Care Studies-I, a single-center, prospective observational study. All acutely admitted patients who were 18 years and older with an expected ICU stay of at least 24 h were eligible for inclusion. All patients underwent clinical examination combined with lung ultrasound, conducted by researchers not involved in patient care. Clinical examination included auscultation of the bilateral regions for crepitations and rhonchi. Lung ultrasound was conducted according to the Bedside Lung Ultrasound in Emergency protocol. Pulmonary edema was defined as three or more B lines in at least two (bilateral) scan sites. An agreement was described by using the Cohen κ coefficient, sensitivity, specificity, negative predictive value, positive predictive value, and overall accuracy. Subgroup analysis were performed in patients who were not mechanically ventilated.

resultsThe Simple Intensive Care Studies-I cohort included 1075 patients, of whom 926 (86%) were eligible for inclusion in this analysis. Three hundred seven of the 926 patients (33%) fulfilled the criteria for pulmonary edema on lung ultrasound. In 156 (51%) of these patients, auscultation was normal. A total of 302 patients (32%) had audible crepitations or rhonchi upon auscultation. From 130 patients with crepitations, 86 patients (66%) had pulmonary edema on lung ultrasound, and from 209 patients with rhonchi, 96 patients (46%) had pulmonary edema on lung ultrasound. The agreement between auscultation findings and lung ultrasound diagnosis was poor (κ statistic 0.25). Subgroup analysis showed that the diagnostic accuracy of auscultation was better in non-ventilated than in ventilated patients.

conclusionThe agreement between lung ultrasound and auscultation is poor.

trial registrationNCT02912624. Registered on September 23, 2016.

Indexed as

AgedAPACHEAuscultationChi-Square DistributionCohort StudiesCritical IllnessFemaleHumansLungMaleMiddle AgedPhysical ExaminationPoint-of-Care SystemsProspective StudiesStatistics, NonparametricStethoscopesAuscultationClinical examinationCritical careDiagnostic accuracyLung ultrasoundProspective studyPulmonary edema

Identifiers

PMID31931844
PMCPMC6958607
OpenAlexW3000447648

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.