ArticleJournal of cardiothoracic surgery2020
Adult ALCAPA: from histological picture to clinical features.
Article in Journal of cardiothoracic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Anomalous left coronary artery from the pulmonary artery in adults: a systematic review of clinical presentation, diagnosis, and outcomes.The international journal of cardiovascular imaging · 2026Pooled it
- Long-Term Systolic and Diastolic Function in Patients with Repaired Anomalous Left Coronary Artery from the Pulmonary Artery.Pediatric cardiology · 2026Article
- Anomalous Coronary Artery Origin from Pulmonary Artery and Coronary Fistulas: A Review About Coronary Steal Phenomenon.Children (Basel, Switzerland) · 2026Review
- Review
- The patient's decision dilemma after screening coronary computed tomography angiography-adult-type ALCAPA with a multimodality imaging approach: a case report.European heart journal. Case reports · 2025Article
- Pulmonary hypertension associated with anomalous left coronary artery originating from the pulmonary artery.ESC heart failure · 2025Article
- The Winding Road to Dyspnea: A Case Report of an Unusual Presentation of Anomalous Left Coronary Artery from the Pulmonary Artery.Reports (MDPI) · 2024Article
- Coronary microvascular dysfunction in childhood: An emerging pathological entity and its clinical implications.American heart journal plus : cardiology research and practice · 2024Article
- Anomalous Left Coronary Artery from the Pulmonary Artery: How to Diagnose and Treat.Journal of personalized medicine · 2023Review
- Clinical manifestations and computed tomography angiography features of anomalous left coronary artery from the pulmonary artery syndrome.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023Article
- Surgical Reconstruction of the Anomalous Left Coronary Artery From the Pulmonary Artery.Texas Heart Institute journal · 2023Article
- Article
- Anomalous Left Coronary Artery Connected to the Pulmonary Artery in a 15-Year-Old Girl: Case Report and Discussion on Secondary Prevention of Sudden Death.Case reports in cardiology · 2021Article
- Life long surveillance is warranted as coronary artery remodels variably after treatment of adult patients with anomalous left coronary artery origin from pulmonary artery.Annals of pediatric cardiologyArticle
- Measures to improve in-hospital outcomes of patients undergoing surgical repair for anomalous origin of left coronary artery from pulmonary artery.Annals of cardiac anaesthesiaObservational
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Authors and funding
22 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital coronary anomaly that results in high mortality if left untreated. Our aim was to extend our knowledge of the histological, angiographic, and clinical characteristics of ALCAPA in order to deepen our understanding of this rare entity. CASE PRESENTATION: We were involved in the assessment, treatment, and pathological evaluation of two adult ALCAPA patients who were rescued from ventricular fibrillation and then surgically treated to establish a dual coronary artery system. Histological studies indicated various chronic ischemic changes in the myocardium, patchy fibrosis, and severely thickened arteriolar walls in both ventricles. The first patient is alive and well 11.5 years after surgical correction without any implantable cardioverter defibrillator (ICD) activations. The second patient required re-do surgery 9 months after the initial operation but subsequently died. Histologically, chronic ischemic alteration of the myocardium and thickened arteriolar walls persisted even after surgical correction, and coronary angiography (CAG) showed an extremely slow flow phenomenon even after surgical correction in both patients. The average postoperative opacification rate in the first case was 7.36 + 1.12 (n = 2) in the RCA, 3.81 + 0.51 (n = 3) in the left anterior descending (LAD) artery, and 4.08 + 0.27 (n = 4) in the left circumflex (LCx) artery. The slow flow phenomenon may represent persistent high arteriolar resistance in both ventricles.
conclusionsSeldom reported or new findings in adult ALCAPA were identified in two cases. More frequent diagnosis of adult ALCAPA can be expected because of the widespread availability of resuscitation and more advanced diagnostic modalities. Accumulation of pathological and clinical findings and confirmation of the long-term follow-up results after treatment may contribute to expanding our knowledge of this rare entity and establishing optimal treatment.
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