SynthesisMalaria journal2020
A systematic review of factors affecting adherence to malaria chemoprophylaxis amongst travellers from non-endemic countries.
Synthesis in Malaria journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Methods to Assess Adult and Adolescent Patients' Adherence to Antimalarial Treatment: A Systematic Review.Frontiers in pharmacology · 2022Pooled it
- Long-Acting Antimalarial Drug Delivery Systems for Chemoprophylaxis: Formulation Strategies and Routes of Administration.Pharmaceutical research · 2026Review
- Comparative efficacy of free and PNAGA-encapsulated antimalarial drugs: temperature-dependent modulation ofFrontiers in pharmacology · 2026Article
- Malaria: 11-Year Experience With Imported Cases at a German University Hospital and Epidemiological Trends Amid the COVID-19 Pandemic.Journal of parasitology research · 2026Article
- Adherence to stand-by emergency treatment and mosquito protection measures in short-term travellers to moderate malaria risk areas.New microbes and new infections · 2025Article
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- Article
- Symptoms of illness during travel and risk factors for non-adherence to malaria prophylaxis-a cross-sectional study in travellers from Germany.Journal of travel medicine · 2023Article
- Creating and Validating Ligase Primers to Detect Single Nucleotide Polymorphisms Associated with Atovaquone Resistance in Plasmodium falciparum.The American journal of tropical medicine and hygiene · 2023Article
- Questionnaire-Based Analysis of Adverse Events and Compliance with Malaria Chemoprophylaxis in Taiwan.Journal of personalized medicine · 2023Article
- Epidemiology and clinical features of imported malaria: a 14-year retrospective single-centre descriptive study in Prague, Czech Republic.Malaria journal · 2022Article
- A PfSPZ vaccine immunization regimen equally protective against homologous and heterologous controlled human malaria infection.NPJ vaccines · 2022Article
- Antimalarial chemoprophylaxis and treatment in the USA: limited access and extreme price variability.Journal of travel medicine · 2022Article
- Forest malaria and prospects for anti-malarial chemoprophylaxis among forest goers: findings from a qualitative study in Thailand.Malaria journal · 2022Article
- Acceptability and feasibility of malaria prophylaxis for forest goers: findings from a qualitative study in Cambodia.Malaria journal · 2021Article
- Contents and quality of travel tips on malaria in English and Spanish travel blogs.Malaria journal · 2021Article
- Medical Advice for Travelers.Deutsches Arzteblatt international · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this systematic review was to identify predictors of actual or intended adherence with malaria chemoprophylaxis amongst travellers from non-endemic countries visiting endemic countries.
methodsA systematic review of the literature was conducted using MEDLINE, Embase, PsycINFO and Global Health databases for studies published up to April 2019. Studies were included if they assessed reasons for adherence among people travelling from a country where malaria was not endemic to a country where it was.
resultsThirty-two studies were included. Predictors of adherence were categorized as relating to either the nature of the travel or the traveller themselves. The three main predictors associated with nature of travel included: destination (e.g. country visited, urban vs rural areas), length of travel and type of travel (e.g. package vs backpacking holiday). The four main traveller-associated predictors were: age, reason for travel (e.g. business, leisure or visiting friends and relatives), perceived risk of catching malaria and experienced or expected medication effects.
conclusionsIn order to improve adherence, clinicians should focus on travellers who are least likely to exhibit adherent behaviour. This includes travellers visiting destinations known to have lower adherence figures (such as rural areas), backpackers, business travellers, younger travellers and those travelling for longer periods of time. They should also check to ensure travellers' perceptions of the risks of malaria are realistic. Where appropriate, misperceptions (such as believing that curing malaria is easier than taking prophylaxis or that travellers visiting relatives have some level of innate immunity) should be corrected. All travellers should be informed of the potential side-effects of medication and given guidance on why it is nonetheless beneficial to continue to take prophylaxis. Further research is required to test interventions to improve adherence.
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Registered trials
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