Evidence map›Paper›PMID 31931798›Full record

Observational studyRespiratory research2020

Extracorporeal membrane oxygenation as a bridge to lung transplantation: analysis of Korean organ transplantation registry (KOTRY) data.

Ryoung-Eun Ko, Jin Gu Lee, Song Yee Kim, Young Tae Kim, Sun Mi Choi, Do Hyung Kim, Woo Hyun Cho, Seung-Il Park, Kyung-Wook Jo, Hong Kwan Kim and 3 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Respiratory research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Impact of pre-transplant veno-venous extracorporeal membrane oxygenation on post-lung transplant infections.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
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  12. Extracorporeal membrane oxygenation and lung transplantation.Indian journal of thoracic and cardiovascular surgery · 2021
    Article
  13. Article
  14. Lung transplantation for severe COVID-19-related ARDS.Therapeutic advances in respiratory disease
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Ryoung-Eun KoDepartment of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Jin Gu LeeDepartment of Thoracic and Cardiovascular Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Song Yee KimDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Young Tae KimDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Sun Mi ChoiDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Do Hyung KimDepartment of Thoracic and Cardiovascular Surgery, Pusan National University YangSan Hospital, Gyeongsangnam-do, Korea.
Woo Hyun ChoDepartment of Pulmonology and Critical Care Medicine, Pusan National University YangSan Hospital, Gyeongsangnam-do, Korea.
Seung-Il ParkDepartment of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Kyung-Wook JoDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Hong Kwan KimDepartment of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Hyo Chae PaikDepartment of Thoracic and Cardiovascular Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Kyeongman JeonDepartment of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. kjeon@skku.edu.ORCID http://orcid.org/0000-0002-4822-1772
Korean Organ Transplantation Registry Study Group
Yonsei University · KRSamsung Medical Center · KRUlsan College · KRSeoul National University Hospital · KR

Funding

Korea Centers for Disease Control and Prevention 2017-ER6301-00#
6 · The paper itself

Abstract

backgroundThe use of extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplantation has greatly increased. However, data regarding the clinical outcomes of this approach are lacking. The objective of this multicenter prospective observational cohort study was to evaluate lung transplantation outcomes in Korean Organ Transplantation Registry (KOTRY) patients for whom ECMO was used as a bridge to transplantation.

methodsBetween March 2015 and December 2017, a total of 112 patients received lung transplantation and were registered in the KOTRY, which is a prospective, multicenter cohort registry. The entire cohort was divided into two groups: the control group (n = 85, 75.9%) and bridge-ECMO group (n = 27, 24.1%).

resultsThere were no significant differences in pre-transplant and intraoperative characteristics except for poorer oxygenation, more ventilator use, and longer operation time in the bridge-ECMO group. The prevalence of primary graft dysfunction at 0, 24, 48, and 72 h after transplantation did not differ between the two groups. Although postoperative hospital stays were longer in the bridge-ECMO group than in the control group, hospital mortality did not differ between the two groups (25.9% vs. 13.3%, P = 0.212). The majority of patients (70.4% of the bridge-ECMO group and 77.6% of the control group) were discharged directly to their homes. Finally, the use of ECMO as a bridge to lung transplantation did not significantly affect overall survival and graft function.

conclusionsShort- and long-term post-transplant outcomes of bridge-ECMO patients were comparable to recipients who did not receive ECMO.

Indexed as

Data AnalysisRegistriesCohort StudiesExtracorporeal Membrane OxygenationFemaleFollow-Up StudiesHumansLung TransplantationMaleMiddle AgedProspective StudiesRepublic of KoreaTreatment OutcomeBridge to transplantExtracorporeal membrane oxygenationsLung transplantationTreatment outcome

Identifiers

PMID31931798
PMCPMC6958687
OpenAlexW2998778898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.