Evidence map›Paper›PMID 31931525›Full record

ArticleAnnals of internal medicine2020

Tenofovir Alafenamide for HIV Preexposure Prophylaxis: What Can We DISCOVER About Its True Value?

Douglas S Krakower, Demetre C Daskalakis, Judith Feinberg, Julia L Marcus

Open access · greenAbstract read
In one paragraph

Article in Annals of internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Association between the geographic accessibility of PrEP and PrEP use among MSM in nonurban areas.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Tenofovir prodrugs potently inhibit Epstein-Barr virus lytic DNA replication by targeting the viral DNA polymerase.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Douglas S KrakowerBeth Israel Deaconess Medical Center, Harvard Medical School, Harvard Pilgrim Health Care Institute, and The Fenway Institute, Boston, Massachusetts (D.S.K.).
Demetre C DaskalakisNew York City Department of Health and Mental Hygiene, New York, New York (D.C.D.).
Judith FeinbergWest Virginia University, Morgantown, West Virginia (J.F.).
Julia L MarcusHarvard Medical School, Harvard Pilgrim Health Care Institute, and The Fenway Institute, Boston, Massachusetts (J.L.M.).
Harvard University · USNew York City Department of Health and Mental Hygiene · USWest Virginia University · US

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Laura F. Gibson · 2012 to 2026
$81.0M
Optimizing Care for HIV/HCV-Coinfected Patients in the New HCV Treatment EraK01AI122853 · NIAID · KAISER FOUNDATION RESEARCH INSTITUTE · PI MARCUS, JULIA L. · 2016 to 2020
$655k
NIAID NIH HHS K01 AI122853NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenineAlanineAnti-HIV AgentsFemaleHIV InfectionsHumansMalePre-Exposure ProphylaxisTenofovirTreatment OutcomeAdenineAlanineAnti-HIV AgentsTenofovirtenofovir alafenamide

Identifiers

PMID31931525
PMCPMC7217716
OpenAlexW3000583542

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.