ArticleRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology2020
Automatic reconstruction of the delivered dose of the day using MR-linac treatment log files and online MR imaging.
Article in Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Development and evaluation of deep learning models for estimating the organ at-risk dose constraint from two-dimensional cine magnetic resonance imaging scans during irradiation.Journal of applied clinical medical physics · 2025Article
- Intra-adaptational changes in online adaptive radiotherapy: from the ideal to the real dose.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Article
- Workflow to detect exceeded dose constraints in pancreatic stereotactic body irradiation after intrafraction motion during magnetic resonance-guided adaptive radiotherapy using a deep learning-refined contour propagation tool.Physics and imaging in radiation oncology · 2025Article
- Towards clinical implementation of T2-weighted cine imaging for intrafraction drift correction workflows on the 1.5 Tesla magnetic resonance-linear accelerator.Physics and imaging in radiation oncology · 2025Article
- First experimental demonstration of magnetic resonance-guided multileaf collimator tracking for (ultra-)hypofractionated prostate radiotherapy.Physics and imaging in radiation oncology · 2025Article
- Development of in-house software to process real-time cine magnetic resonance images acquired during 1.5 T MR-guided radiation therapy.Scientific reports · 2025Article
- Prostate motion in magnetic resonance imaging-guided radiotherapy and its impact on margins.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Article
- Impact of log file source and data frequency on accuracy of log file-based patient specific quality assurance.Zeitschrift fur medizinische Physik · 2025Article
- Automated daily dose accumulation workflow for treatment quality assurance during online adaptive radiotherapy with a 0.35T MR-linac.Journal of applied clinical medical physics · 2025Article
- Monte Carlo dose calculation for photon and electron radiotherapy on dynamically deforming anatomy.Medical physics · 2025Article
- Added value of non-rigid image registration for intrafraction dose accumulation in magnetic resonance imaging-guided prostate radiotherapy.Physics and imaging in radiation oncology · 2025Article
- Treatment planning evaluation and experimental validation of the magnetic resonance-based intrafraction drift correction.Physics and imaging in radiation oncology · 2024Article
- Adaptive ultra-hypofractionated whole-pelvic radiotherapy in high-risk and very high-risk prostate cancer on 1.5-Tesla MR-Linac: Estimated delivered dose and early toxicity results.Chronic diseases and translational medicine · 2024Article
- Respiratory motion modelling for MR-guided lung cancer radiotherapy: model development and geometric accuracy evaluation.Physics in medicine and biology · 2024Article
- Impact of technological advances in treatment planning, image guidance, and treatment delivery on target margin design for prostate cancer radiotherapy: an updated review.The British journal of radiology · 2024Review
- Investigation of autosegmentation techniques on T2-weighted MRI for off-line dose reconstruction in MR-linac workflow for head and neck cancers.Medical physics · 2024Article
- Magnetic resonance image-guided adaptive radiotherapy enables safe CTV-to-PTV margin reduction in prostate cancer: a cine MRI motion study.Frontiers in oncology · 2024Article
- Online adaptive radiotherapy and dose delivery accuracy: A retrospective analysis.Journal of applied clinical medical physics · 2023Article
- Accelerating 4D image reconstruction for magnetic resonance-guided radiotherapy.Physics and imaging in radiation oncology · 2023Article
- Assessment of intrafractional prostate motion and its dosimetric impact in MRI-guided online adaptive radiotherapy with gating.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023Article
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12 authors.
Funding
Abstract
background and purposeAnatomical changes during external beam radiotherapy prevent the accurate delivery of the intended dose distribution. Resolving the delivered dose, which is currently unknown, is crucial to link radiotherapy doses to clinical outcomes and ultimately improve the standard of care. MATERIAL AND
methodsIn this study, we present a dose reconstruction workflow based on data routinely acquired during MR-guided radiotherapy. It employs 3D MR images, 2D cine MR images and treatment machine log files to calculate the delivered dose taking intrafractional motion into account. The developed pipeline was used to measure anatomical changes and assess their dosimetric impact in 89 prostate radiotherapy fractions delivered with a 1.5 T MR-linac at our institute.
resultsOver the course of radiation delivery, the CTV shifted 0.6 mm ± 2.1 mm posteriorly and 1.3 mm ± 1.5 mm inferiorly. When extrapolating the dose changes in each case to 20 fractions, the mean clinical target volume D
conclusionsThe presented end-to-end workflow is able to reliably, non-invasively and automatically reconstruct the delivered prostate radiotherapy dose by processing MR-linac treatment log files and online MR images. In the future, we envision this workflow to be adapted to other cancer sites and ultimately to enter widespread clinical use.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.