Evidence map›Paper›PMID 31930993›Full record

Trial reportAmerican journal of obstetrics and gynecology2020

Health resource utilization of labor induction versus expectant management.

William A Grobman, Grecio Sandoval, Uma M Reddy, Alan T N Tita, Robert M Silver, Gail Mallett, Kim Hill, Madeline Murguia Rice, Yasser Y El-Sayed, Ronald J Wapner and 13 more

Open access · greenAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in American journal of obstetrics and gynecology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Induction of labour at or beyond 37 weeks' gestation.The Cochrane database of systematic reviews · 2020
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Head in the sand: Contemporary Australian attitudes towards induction of labour.The Australian & New Zealand journal of obstetrics & gynaecology · 2022
    Article
  10. Observational
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 19 institutions in 2 countries.

William A GrobmanDepartments of Obstetrics and Gynecology, Northwestern University, Chicago, IL. Electronic address: w-grobman@northwestern.edu.
Grecio SandovalGeorge Washington University Biostatistics Center, Washington, DC.
Uma M ReddyEunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.
Alan T N TitaUniversity of Alabama at Birmingham, Birmingham, AL.
Robert M SilverUniversity of Utah Health Sciences Center, Salt Lake City, UT.
Gail MallettDepartments of Obstetrics and Gynecology, Northwestern University, Chicago, IL.
Kim HillUniversity of Utah Health Sciences Center, Salt Lake City, UT.
Madeline Murguia RiceGeorge Washington University Biostatistics Center, Washington, DC.
Yasser Y El-SayedStanford University, Stanford, CA.
Ronald J WapnerColumbia University, New York, NY.
Dwight J RouseBrown University, Providence, RI.
George R SaadeUniversity of Texas Medical Branch, Galveston, TX.
John M ThorpUniversity of North Carolina at Chapel Hill, Chapel Hill, NC.
Suneet P ChauhanUniversity of Texas Health Science Center at Houston-Children's Memorial Hermann Hospital, Houston, TX.
Jay D IamsOhio State University, Columbus, OH.
Edward K ChienMetroHealth Medical Center-Case Western Reserve University, Cleveland, OH.
Brian M CaseyUniversity of Texas Southwestern Medical Center, Dallas, TX.
Ronald S GibbsUniversity of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO.
Sindhu K SrinivasUniversity of Pennsylvania, Philadelphia, PA.
Geeta K SwamyDuke University, Durham, NC.
Hyagriv N SimhanUniversity of Pittsburgh, Pittsburgh, PA.
George A MaconesWashington University, Saint Louis, MO.
Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units (MFMU) Network
The Ohio State University · USUniversity of Colorado Anschutz Medical Campus · USGeorge Washington University · USNorthwestern University · USThe University of Texas Medical Branch at Galveston · USUniversity of Utah · USWashington University in St. Louis · USBrown University · USColumbia University · USDuke University · USEunice Kennedy Shriver Center · USMemorial Hermann · USMetroHealth Medical Center · USStanford University · USThe University of Texas Southwestern Medical Center · USUniversity of Alabama at Birmingham · USUniversity of North Carolina at Chapel Hill · USUniversity of Pennsylvania · USUniversity of Pittsburgh · US

Funding

Data Coord Ctr-NICHD Cooperative Multicenter Maternal Medicine Units Research NetU10HD036801 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI CLIFTON, REBECCA GERSNOVIEZ · 2009 to 2021
$174.2M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
SARS-CoV-2 Vaccine Pregnancy RegistryU24HD036801 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI Rebecca Gersnoviez Clifton · 2021 to 2026
$39.2M
MATERNAL FETAL RESEARCH NETWORK: DATA COORDINATING CTRU01HD036801 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI THOM, ELIZABETH ANN · 1998 to 2008
$27.0M
NICHD Maternal Fetal Medicine Units NetworkU10HD034116 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI CASEY, BRIAN M · 1996 to 2015
$19.3M
NICHD Maternal Fetal Medicine Units NetworkU10HD034208 · NICHD · UNIVERSITY OF UTAH · PI VARNER, MICHAEL W. · 1996 to 2015
$16.6M
NICHD Maternal Fetal Medicine Units NetworkU10HD027869 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TITA, ALAN THEVENET N. · 1991 to 2015
$12.8M
NICHD Maternal Fetal Medicine Units NetworkU10HD040485 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WAPNER, RONALD · 2001 to 2015
$12.5M
NICHD Maternal Fetal Medicine Units NetworkU10HD040560 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI THORP, JOHN M · 2001 to 2015
$10.3M
NICHD Maternal Fetal Medicine Units NetworkU10HD040512 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GROBMAN, WILLIAM ADAM · 2001 to 2015
$8.7M
NICHD Maternal Fetal Medicine Units NetworkU10HD027915 · NICHD · OHIO STATE UNIVERSITY · PI IAMS, JAY · 1992 to 2015
$7.7M
NCATS NIH HHS UL1 TR001863NCATS NIH HHS UL1 TR001873NICHD NIH HHS U01 HD036801NICHD NIH HHS U10 HD027869NICHD NIH HHS U10 HD027915NICHD NIH HHS U10 HD034116NICHD NIH HHS U10 HD034208NICHD NIH HHS U10 HD036801NICHD NIH HHS U10 HD040485NICHD NIH HHS U10 HD040500NICHD NIH HHS U10 HD040512NICHD NIH HHS U10 HD040544NICHD NIH HHS U10 HD040545NICHD NIH HHS U10 HD040560NICHD NIH HHS U10 HD053097NICHD NIH HHS U10 HD068258NICHD NIH HHS U10 HD068268NICHD NIH HHS U10 HD068282NICHD NIH HHS U24 HD036801NICHD NIH HHS UG1 HD027869NICHD NIH HHS UG1 HD027915NICHD NIH HHS UG1 HD034116NICHD NIH HHS UG1 HD034208NICHD NIH HHS UG1 HD040485NICHD NIH HHS UG1 HD040500NICHD NIH HHS UG1 HD040512NICHD NIH HHS UG1 HD040544NICHD NIH HHS UG1 HD040545NICHD NIH HHS UG1 HD040560NICHD NIH HHS UG1 HD053097NICHD NIH HHS UG1 HD068258NICHD NIH HHS UG1 HD068268NICHD NIH HHS UG1 HD068282NICHD NIH HHS UG1 HD087192NICHD NIH HHS UG1 HD087230
6 · The paper itself

Abstract

backgroundAlthough induction of labor of low-risk nulliparous women at 39 weeks reduces the risk of cesarean delivery compared with expectant management, concern regarding more frequent use of labor induction remains, given that this intervention historically has been thought to incur greater resource utilization.

objectiveThe objective of the study was to determine whether planned elective labor induction at 39 weeks among low-risk nulliparous women, compared with expectant management, was associated with differences in health care resource utilization from the time of randomization through 8 weeks postpartum. STUDY

designThis is a planned secondary analysis of a multicenter randomized trial in which low-risk nulliparous women were assigned to induction of labor at 39 weeks or expectant management. We assessed resource utilization after randomization in 3 time periods: antepartum, delivery admission, and discharge through 8 weeks postpartum.

resultsOf 6096 women with data available, those in the induction of labor group (n = 3059) were significantly less likely in the antepartum period after randomization to have at least 1 ambulatory visit for routine prenatal care (32.4% vs 68.4%), unanticipated care (0.5% vs 2.6%), or urgent care (16.2% vs 44.3%), or at least 1 antepartum hospitalization (0.8% vs 2.2%, P < .001 for all). They also had fewer tests (eg, sonograms, blood tests) and treatments (eg, antibiotics, intravenous hydration) prior to delivery. During the delivery admission, women in the induction of labor group spent a longer time in labor and delivery (median, 0.83 vs 0.57 days), but both women (P = .002) and their neonates (P < .001) had shorter postpartum stays. Women and neonates in both groups had similar frequencies of postpartum urgent care and hospital readmissions (P > .05 for all).

conclusionWomen randomized to induction of labor had longer durations in labor and delivery but significantly fewer antepartum visits, tests, and treatments and shorter maternal and neonatal hospital durations after delivery. These results demonstrate that the health outcome advantages associated with induction of labor are gained without incurring uniformly greater health care resource use.

Indexed as

AdultAmbulatory CareAnti-Bacterial AgentsFemaleFluid TherapyGestational AgeHealth ResourcesHematologic TestsHumansInfant, NewbornLabor, InducedLength of StayPatient ReadmissionPeripartum PeriodPregnancyPrenatal CareAnti-Bacterial Agentscesarean deliverycostsexpectant managementinduction of laborresources

Identifiers

PMID31930993
PMCPMC7141954
OpenAlexW2999593232

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.