Observational studyJournal of surgical oncology2020
The association of preoperative anxiety and depression with neurocognitive disorder following oncological surgery.
Observational study in Journal of surgical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Psychological factors associated with postoperative cognitive outcomes in older adults: a systematic review and meta-analysis.British journal of anaesthesia · 2026Pooled it
- Effect of dexmedetomidine on postoperative cognitive function in patients with gastrointestinal cancer: a meta-analysis of randomized controlled trials.Frontiers in neurologyPooled it
- Effects of Intravenous Analgesia Using Tramadol on Postoperative Depression State and Sleep Quality in Women Undergoing Abdominal Endoscopic Surgery: A Randomized Controlled Trial.Drug design, development and therapy · 2022Trial
- Evidence summary: Prehabilitation strategies for patients with primary liver cancer.Asia-Pacific journal of oncology nursing · 2025Review
- Astrocyte morphological remodeling regulates consciousness state transitions induced by inhaled general anesthesia.Molecular psychiatry · 2025Article
- Co-occurrence of CT-based radiological sarcopenia and frailty are related to impaired survival in surgical oncology.The British journal of radiology · 2025Article
- Impact of preoperative anxiety and depressive symptoms on clinical outcomes of anterior talofibular ligament reconstruction surgery.Frontiers in psychiatry · 2025Article
- [Perioperative anxiety and fear of death].Die Anaesthesiologie · 2023Review
- The association between the inflammatory response following surgery and post-operative delirium in older oncological patients: a prospective cohort study.Age and ageing · 2022Article
- Mild acute stress prevents the memory impairment induced by long-term isoflurane anesthesia.Translational neuroscience · 2022Article
- Relationship Between Depression/Anxiety and Cognitive Function Before and 6 Weeks After Major Non-Cardiac Surgery in Older Adults.Journal of geriatric psychiatry and neurology · 2022Observational
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- Incidence of postoperative cognitive dysfunction in older women undergoing pelvic organ prolapse surgery.International urogynecology journal · 2021Article
- The association of preoperative anxiety and depression with neurocognitive disorder following oncological surgery.Journal of surgical oncology · 2020Observational
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe proposed underlying mechanisms of anxiety and depression, and of postoperative neurocognitive disorder (NCD), each include immune system involvement. Therefore, the aims of this study were to investigate the incidence of postoperative NCD 3 months after surgery among oncological patients undergoing surgery and to evaluate the role of preoperative anxiety and depression.
methodA consecutive series of patients (age ≥ 18 years) undergoing surgery for the removal of solid tumors were included (n = 218). Cognitive performance was assessed preoperatively and at 3 months postoperatively. Preoperative anxiety and depression were evaluated using the Hospital Anxiety and Depression Scale.
resultsNCD affected 12.3% of elderly patients (age ≥ 70 years, n = 57) at 3 months after surgery, with executive function mostly affected. By contrast, 8.4% of younger patients (age < 70 years, n = 107) were affected, with information processing speed mostly affected. Low educational attainment was a risk factor (OR, 6.0; 95% CI, 1.9-19.0) of overall NCD, whereas preoperative anxiety was associated with decline in the domain of executive function.
conclusionPostoperative NCD is a complication of oncological surgery for all adults instead of the elderly only. Preoperative anxiety was associated with an increased risk of executive function decline, and low educational attainment was a key factor for overall NCD.
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