Evidence map›Paper›PMID 31930443›Full record

ArticleNano convergence2020

Direct electrophoretic microRNA preparation from clinical samples using nanofilter membrane.

Kidan Lee, Jae-Hyun Kang, Hyun-Mi Kim, Junhyoung Ahn, Hyungjun Lim, JaeJong Lee, Wan-Jin Jeon, Jae-Hoon Lee, Ki-Bum Kim

Abstract read
In one paragraph

Article in Nano convergence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kidan LeeDepartment of Materials Science and Engineering, Seoul National University, Seoul, 08826, Republic of Korea.
Jae-Hyun KangDepartment of Materials Science and Engineering, Seoul National University, Seoul, 08826, Republic of Korea.
Hyun-Mi KimResearch Institute of Advanced Materials, Seoul National University, Seoul, 08826, Republic of Korea.
Junhyoung AhnDepartment of Nano Manufacturing Technology, Nano Convergence Mechanical Systems Research Division, Korea Institute of Machinery & Materials (KIMM), Daejeon, 34103, Republic of Korea.
Hyungjun LimDepartment of Nano Manufacturing Technology, Nano Convergence Mechanical Systems Research Division, Korea Institute of Machinery & Materials (KIMM), Daejeon, 34103, Republic of Korea.
JaeJong LeeDepartment of Nano Manufacturing Technology, Nano Convergence Mechanical Systems Research Division, Korea Institute of Machinery & Materials (KIMM), Daejeon, 34103, Republic of Korea.
Wan-Jin JeonHeimbiotek Inc., Seongnam, Gyeonggi-do, 13486, Republic of Korea.
Jae-Hoon LeeHeimbiotek Inc., Seongnam, Gyeonggi-do, 13486, Republic of Korea.
Ki-Bum KimDepartment of Materials Science and Engineering, Seoul National University, Seoul, 08826, Republic of Korea. kibum@snu.ac.kr.ORCID http://orcid.org/0000-0003-1392-5021

Funding

Ministry of Science and ICT (KR) 2013M3A6B2078943Ministry of Science and ICT (KR) 2015M3A7B4050454Ministry of Science and ICT (KR) 2019R1A2C2005783
6 · The paper itself

Abstract

A method to directly collect negatively charged nucleic acids, such as DNA and RNA, in the biosamples simply by applying an electric field in between the sample and collection buffer separated by the nanofilter membrane is proposed. The nanofilter membrane was made of low-stress silicon nitride with a thickness of 100 nm, and multiple pores were perforated in a highly arranged pattern using nanoimprint technology with a pore size of 200 nm and a pore density of 7.22 × 10

Indexed as

Liquid biopsymiRNA extractionNanofiltrationNanoporous membraneNucleic acid extractionNucleic acid preparation

Identifiers

PMID31930443
PMCPMC6955385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.