ArticleInternational ophthalmology2020
Factors influencing the reduction in corneal endothelial cells after Ex-Press
Article in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Ab interno removal of malpositioned ex-press glaucoma device combined with bleb needling.Japanese journal of ophthalmology · 2025Article
- Utility of intraoperative optical coherence tomography in filtration surgery using MicroShunt.Japanese journal of ophthalmology · 2025Observational
- Systematic Literature Reviews Comparing the Long-Term Safety Outcomes for the Port Delivery System with Ranibizumab (PDS) Versus Other Ocular Implants.Ophthalmology and therapy · 2024Review
- Corneal endothelial density loss in patients after gonioscopy‑assisted transluminal trabeculotomy.International ophthalmology · 2024Article
- Corneal endothelial cell loss after EX-PRESS surgery depends on site of insertion, cornea or trabecular meshwork.International ophthalmology · 2023Article
- Improvement of the loss of corneal endothelial cells by relocating the tip of the Baerveldt® implant tube from the anterior chamber to the vitreous cavity.International ophthalmology · 2023Article
- Ex-PRESS® surgery versus trabeculectomy for primary open-angle glaucoma with low preoperative intraocular pressure.International ophthalmology · 2022Article
- Long-Term Changes in Corneal Endothelial Cell Density after Ex-PRESS Implantation: A Contralateral Eye Study.Journal of clinical medicine · 2022Article
- Corneal Edema and Keratoplasty: Risk Factors in Eyes With Previous Glaucoma Drainage Devices.American journal of ophthalmology · 2022Article
- Corneal Endothelial Cell Loss in Patients After Minimally Invasive Glaucoma Surgery: Current Perspectives.Clinical ophthalmology (Auckland, N.Z.) · 2022Review
- Evaluation of the Effect of the First Generation iStent on Corneal Endothelial Cell Loss-A Match Case-Control Study.Journal of clinical medicine · 2021Article
- Ex-PressInternational ophthalmology · 2021Article
- Short-term endothelial cell density changes after gonioscopy-assisted transluminal trabeculotomy.Arquivos brasileiros de oftalmologia · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe investigated the factors that influence the reduction in corneal endothelial cells after Ex-Press
methodsThis was a retrospective study. We included patients who had undergone Ex-Press surgery and were followed up for > 2. We analyzed the corneal endothelial cell density (ECD) before and after Ex-Press surgery. We investigated the insertion position (Ex-Press device was inserted into cornea or trabecular meshwork (TM)), Ex-Press-iris touch, cornea-iris touch, peripheral anterior synechiae, history of trabeculotomy, history of selective laser trabeculoplasty, type of glaucoma, and simultaneous cataract surgery as influencing factors. We used multivariate analysis to determine the factors influencing the reduction rate of ECD.
resultsWe included 129 eyes. The mean of ECD had decreased 7.0% at 2 years. Ex-Press surgeries significantly decreased the ECD after 2 years (p = 0.0118). As a result of the multivariate analysis, the factor that led to a significantly faster reduction in ECD was the insertion position of the Ex-Press (p < 0.0001). The reduction rate of ECD after 2 years in cases of insertion into the cornea (27 eyes) was 15.1 ± 3.6%, and in cases of insertion into a TM (102 eyes), it was 5.2 ± 1.4%.
conclusionsInsertion into the cornea was a risk factor for rapid ECD loss. The Ex-Press should be inserted into a TM for long-term protection of the corneal endothelial cells.
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