Evidence map›Paper›PMID 31930431›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2020

β-Sitosterol attenuates carbon tetrachloride-induced oxidative stress and chronic liver injury in rats.

Ezhilarasan Devaraj, Anitha Roy, Geetha Royapuram Veeraragavan, Anitha Magesh, Aneymol Varikalam Sleeba, Lakshminarayanan Arivarasu, Brundha Marimuthu Parasuraman

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Frontiers in pharmacology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Sterols in Inflammatory Diseases: Implications and Clinical Utility.Advances in experimental medicine and biology · 2024
    Review
  19. Amylase-producing marine actinobacterium ofJournal of advanced pharmaceutical technology & research · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ezhilarasan DevarajDepartment of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, 600 077, India. ezhild@gmail.com.ORCID 0000-0002-5068-2383
Anitha RoyDepartment of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, 600 077, India.
Geetha Royapuram VeeraragavanDepartment of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, 600 077, India.
Anitha MageshDepartment of Research and Development, Saveetha Institute of Medical and Technical Sciences, Chennai, 602 105, India.
Aneymol Varikalam SleebaDepartment of Microbiology, St. Xavier's College for Women, Aluva, Kerala, 683101, India.
Lakshminarayanan ArivarasuDepartment of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, 600 077, India.
Brundha Marimuthu ParasuramanDepartment of Pathology, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, 600 077, India.
Saveetha University · INSt. Xavier's College (Autonomous)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic liver diseases are clinically silent and responsible for significant morbidity and mortality worldwide. β-Sitosterol (BSS), major phytosterol in plants, has a wide spectrum of protective effect against various chronic ailments. We investigated the hepatoprotective effect of BSS against carbon tetrachloride (CCl

Indexed as

AnimalsCarbon TetrachlorideChemical and Drug Induced Liver InjuryLipid PeroxidationLiverMaleMatrix Metalloproteinase 9Oxidative StressRatsRats, WistarSitosterolsCarbon Tetrachloridegamma-sitosterolMatrix Metalloproteinase 9SitosterolsChronic liver diseasesHepatic fibrosisOxidative stressPhytosterolsα-SMA

Identifiers

PMID31930431
OpenAlexW3000489693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.