Evidence map›Paper›PMID 31930174›Full record

ArticleWellcome open research2019

Cost-effectiveness of oral versus intravenous antibiotics (OVIVA) in patients with bone and joint infection: evidence from a non-inferiority trial.

Nicola McMeekin, Claudia Geue, Andrew Briggs, Ines Rombach, Ho Kwong Li, Philip Bejon, Martin McNally, Bridget L Atkins, Jamie Ferguson, Matthew Scarborough and 1 more

Open access · goldAbstract read
In one paragraph

Article in Wellcome open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Enhanced macromolecule bioavailability in rats and pigs using an in situ forming synthetic epithelial lining.Journal of controlled release : official journal of the Controlled Release Society · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Current Concepts of Fracture-Related Infection.International journal of clinical practice · 2023
    Review
  16. Article
  17. Article
  18. Review
  19. The Impact of Surgical Strategy and Rifampin on Treatment Outcome in Cutibacterium Periprosthetic Joint Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Nicola McMeekinHEHTA, Institute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.ORCID https://orcid.org/0000-0003-2918-8820
Claudia GeueHEHTA, Institute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.
Andrew BriggsHEHTA, Institute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.
Ines RombachNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, OX3 7LD, UK.ORCID https://orcid.org/0000-0003-3464-3867
Ho Kwong LiDivision of Infectious Diseases, Imperial College London, London, W12 0NN, UK.ORCID https://orcid.org/0000-0002-8149-5943
Philip BejonOxford University Hospitals NHS Foundation Trust, University of Oxford, Oxford, OX3 7HE, UK.ORCID https://orcid.org/0000-0002-2135-7549
Martin McNallyThe Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, Oxford, OX3 7HE, UK.ORCID https://orcid.org/0000-0003-2003-9044
Bridget L AtkinsOxford University Hospitals NHS Foundation Trust, University of Oxford, Oxford, OX3 7HE, UK.ORCID https://orcid.org/0000-0001-8778-0633
Jamie FergusonOxford University Hospitals NHS Foundation Trust, University of Oxford, Oxford, OX3 7HE, UK.
Matthew ScarboroughOxford University Hospitals NHS Foundation Trust, University of Oxford, Oxford, OX3 7HE, UK.ORCID https://orcid.org/0000-0002-0455-0785
OVIVA collaborators
University of Oxford · GBUniversity of Glasgow · GBNuffield Orthopaedic Centre · GBKenya Medical Research Institute · KE

Funding

Department of Health 11/36/29Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antibioticscost-effectivenesseconomic evaluationintravenousnon-inferiorityoral

Identifiers

PMID31930174
PMCPMC6944252
OpenAlexW2956366322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.