Evidence map›Paper›PMID 31930172›Full record

ArticleJournal of clinical pathways : the foundation of value-based care2019

Use of biomarker testing in lung cancer among Puerto Rico and Florida Physicians: Results of a comparative study.

Teresita Muñoz-Antonia, Vani N Simmons, Steven K Sutton, Matthew B Schabath, Iffat Alam, Alberto Chiappori, Gwendolyn P Quinn

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical pathways : the foundation of value-based care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 70% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Teresita Muñoz-AntoniaTumor Biology Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL.
Vani N SimmonsDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL.
Steven K SuttonDepartment of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL.
Matthew B SchabathThoracic Oncology Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL.
Iffat AlamDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL.
Alberto ChiapporiThoracic Oncology Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL.
Gwendolyn P QuinnDepartments of OB-GYN, Population Health and Center for Medical Ethics, New York University School of Medicine, New York, NY.
Moffitt Cancer Center · US

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI Christine O'Connell · 1998 to 2026
$93.5M
NCI NIH HHS P30 CA076292
6 · The paper itself

Abstract

backgroundLung cancer biomarker-driven therapies are the gold standard of treatment and recent studies suggest a higher prevalence of specific targetable biomarkers among Hispanic/Latinos (H/L) than Non-Hispanic Whites (NHW). The study aimed (1) to identify Florida (FL) and Puerto Rico (PR) physicians' knowledge and perceived value of newer genomic data regarding race/ethnicity in relation to optimal lung cancer treatment and survival; and (2) to identify modifiable practice barriers both across and within each location regarding biomarker testing in lung cancer.

methodsA 25-item survey was administered to a stratified random sample of physicians in FL and PR (medical oncologists, radiation oncologists, pulmonologists, and pathologists). Questions targeted domains of biomarker knowledge, attitudes toward testing, barriers, and practice behaviors regarding lung cancer biomarker testing.

resultsThe response rate was 45%. Participants identified guiding treatment decisions (82%) and personalizing treatments for patients (78%) as key benefits to mutation testing. PR physicians were more likely (p=0.022) to believe H/L had an elevated incidence of targetable epidermal growth factor receptor (

conclusionsPractice behaviors differed by specialty and between locations, and differences were noted concerning physician's preferences for ordering mutation testing, indicating a clear need for education among physicians in both locations. IMPACT: Educating physicians regarding biomarker testing is imperative to improve patient care.

Indexed as

biomarker testinghealthcareNon-Small Cell Lung Cancerphysician response

Identifiers

PMID31930172
PMCPMC6953751
OpenAlexW3005187251

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.