ArticleBladder cancer (Amsterdam, Netherlands)2019
Evaluation of Hematuria in a Large Public Health Care System.
Article in Bladder cancer (Amsterdam, Netherlands), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Advancing bladder cancer detection: commentary on a urinary DNA methylation diagnostic assay.Translational andrology and urology · 2026Article
- Isotretinoin-Induced Hematuria in Acne Patients: Frequency, Risk Factors, and Management Recommendations from a Single-Center Study.Dermatology practical & conceptual · 2026Article
- Health-seeking behavior among hematuria patients in Jordan: the case of the Health Belief Model.Frontiers in public health · 2026Article
- Urinary bladder cancer needs more attention - recommendations for health care professionals and politicians in the European Union.Nature reviews. Urology · 2026Review
- Review
- Analyzing Online Search Trends for Kidney, Prostate, and Bladder Cancers in China: Infodemiology Study Using Baidu Search Data (2011-2023).JMIR cancer · 2025Article
- Isolated microhematuria in potential kidney donors: evaluating kidney biopsy findings with dipstick urinalysis and urine microscopy results.Clinical kidney journal · 2025Article
- Urinary microbiome dysbiosis is associated with an inflammatory environment and perturbed fatty acids metabolism in the pathogenesis of bladder cancer.Journal of translational medicine · 2024Article
- Unexplained hematuria in direct oral anticoagulant use: a single-center retrospective case series.Research and practice in thrombosis and haemostasis · 2024Article
- Prevalence and associated factors for asymptomatic microscopic hematuria in adults in the PERSIAN Guilan cohort study (PGCS).Scientific reports · 2024Article
- Discrepant guidelines in the evaluation of hematuria.Abdominal radiology (New York) · 2024Article
- Bladder cancer.Nature reviews. Disease primers · 2023Review
- What is the relative risk of urologic malignancy in microscopic hematuria patients after negative evaluation? A long-term population-based retrospective analysis of 8465 patients.Abdominal radiology (New York) · 2023Article
- Novel urine-based DNA methylation biomarkers for urothelial bladder carcinoma detection in patients with hematuria.Arab journal of urology · 2023Article
- Epidemiologic Profile of Microscopic Hematuria in Iran: A Systematic Review and Meta-Analysis.Iranian journal of public health · 2022Review
- Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundHematuria is the most common presenting symptom in bladder cancer, but many patients are not adequately evaluated.
objectivesTo evaluate the type and frequency of hematuria evaluation in a large public health care system. PATIENTS AND
methodsElectronic medical records of adult patients with urinalysis positive for hematuria (≥3 RBCs/HPF) from January 2015 to April 2018 in an outpatient setting were reviewed. Logistic regression was performed to determine factors associated with urology referral and complete evaluation.
results11,422 patients met the inclusion criteria; the majority were females (72%) and white race (60%). There were an additional 3,221 patient's with initial diagnosis of UTI. Median age was 49.0 years. Testing included repeat urinalysis (50%), imaging (26%), urology referral (11.4%), cystoscopy (4.4%) and complete evaluation defined as cystoscopy and US/CT/MRI (4%). In the multivariable analysis, factors independently associated with higher referral to urology were age >35, male gender, hypertension, RBCs ≥20. African American race was associated with less referral to urology. Smoking was a significant variable on univariable analysis only. 37 patients (0.25%) were diagnosed with urological malignancies, with bladder cancer in 33, 12 of whom are missed by excluding UTI patients.
conclusionsIn the outpatient setting of a public health care system, the vast majority of patients with hematuria are not referred and evaluated properly across all age categories and regardless of smoking status. This might result in missed cancer diagnoses and requires quality improvement measures.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.