Evidence map›Paper›PMID 31930149›Full record

ArticleJournal of immunology research2019

Da-Yong Zhang, Zheng-Yang Pan, Xiong-Kai Yu, Yi-Fan Chen, Chen-Hao Gao, Yu-Tian Yang, Xue-Fan Jiang, Na Li, Jian-Ping Pan

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Da-Yong ZhangDepartment of Clinical Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.ORCID https://orcid.org/0000-0003-1537-1704
Zheng-Yang PanDepartment of Clinical Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Xiong-Kai YuDepartment of Clinical Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Yi-Fan ChenDepartment of Clinical Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Chen-Hao GaoDepartment of Clinical Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Yu-Tian YangDepartment of Clinical Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Xue-Fan JiangDepartment of Otorhinolaryngology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, China.
Na LiDepartment of Clinical Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.
Jian-Ping PanDepartment of Clinical Medicine, School of Medicine, Zhejiang University City College, Hangzhou 310015, China.ORCID https://orcid.org/0000-0001-9636-1561
Zhejiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunosenescence comprises a set of dynamic changes occurring in innate and adaptive immune systems, and macrophage aging plays an important role in innate and adaptive immunosenescence. However, function and polarization changes in aging macrophages have not been fully evaluated, and no effective method for delaying macrophage senescence is currently available. The results of this study reveal that D-galactose (D-gal) can promote J774A.1 macrophage senescence and induce macrophage M1 polarization differentiation.

Indexed as

AnimalsBifidobacterium animalisCell DifferentiationCell ProliferationCells, CulturedCellular SenescenceGalactoseInflammationInterleukin-10Interleukin-12Interleukin-6Macrophage ActivationMacrophagesMiceReactive Oxygen SpeciesSTAT1 Transcription FactorGalactoseInterleukin-10Interleukin-12Interleukin-6Reactive Oxygen SpeciesStat1 protein, mouseSTAT1 Transcription FactorStat6 protein, mouseSTAT6 Transcription Factor

Identifiers

PMID31930149
PMCPMC6942849
OpenAlexW2996011323

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.