Evidence map›Paper›PMID 31929877›Full record

ArticleBiomedical reports2020

Serum parathyroid hormone levels in patients with chronic right heart failure.

Gang-Yong Wu, Qin Shen, Ting Wu, Yi-Cheng Shi, Tian-Xiao Wang, Gang-Jun Zong, Xiang-Jun Yang

Open access · diamondAbstract read
In one paragraph

Article in Biomedical reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gang-Yong WuDepartment of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215002, P.R. China.
Qin ShenDepartment of Cardiology, The 904th Hospital of the People's Liberation Army Joint Logistics Support Force, Wuxi, Jiangsu 214044, P.R. China.
Ting WuDepartment of Cardiology, The 904th Hospital of the People's Liberation Army Joint Logistics Support Force, Wuxi, Jiangsu 214044, P.R. China.
Yi-Cheng ShiDepartment of Cardiology, The 904th Hospital of the People's Liberation Army Joint Logistics Support Force, Wuxi, Jiangsu 214044, P.R. China.
Tian-Xiao WangDepartment of Cardiology, The 904th Hospital of the People's Liberation Army Joint Logistics Support Force, Wuxi, Jiangsu 214044, P.R. China.
Gang-Jun ZongDepartment of Cardiology, The 904th Hospital of the People's Liberation Army Joint Logistics Support Force, Wuxi, Jiangsu 214044, P.R. China.
Xiang-Jun YangDepartment of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215002, P.R. China.
First Affiliated Hospital of Soochow University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parathyroid hormone (PTH) is a novel cardiovascular biomarker which is particularly useful for detection and assessment of heart failure (HF). However, previous studies examining PTH in heart failure have primarily focused on left HF; thus, the relationship between PTH and right HF remains unclear. The aim of the present study was to evaluate the serum PTH levels in patients with chronic right HF. A total of 154 patients with chronic right HF were enrolled in the present study. A binary logistic regression analysis model was used to assess the independent predictive value of PTH levels in chronic right HF. Partial correlative analysis was used to demonstrate the relevance of PTH levels on the parameters of assessment of right heart function. A multiple linear regression analysis model was used to evaluate the independent factors of PTH levels in patients with right HF. The results showed that the serum PTH levels in the right HF group were significantly higher compared with the control group. After adjusting for predictors of right HF, serum PTH levels were associated with right HF with an odds ratio of 1.066 (95% confidence interval: 1.030-1.102, P<0.001. Serum PTH levels were independently correlated with plasma N-terminal pro-B-type natriuretic peptide levels, right ventricular end-diastolic diameter and severity of lower extremity edema (all P<0.05). Therefore, based on the results of the present study, PTH may be a useful biomarker for detection and assessment of right HF.

Indexed as

N-terminal pro-B-type natriuretic peptideparathyroid hormoneright heart failureright ventricletricuspid regurgitation

Identifiers

PMID31929877
PMCPMC6951227
OpenAlexW2993086127

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.