ReviewOxidative medicine and cellular longevity2019
Oxidative Stress-Related Endothelial Damage in Vascular Depression and Vascular Cognitive Impairment: Beneficial Effects of Aerobic Physical Exercise.
Review in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Association Between Physical Activity, Heart Rate Variability and Major Depressive Disorders: An Umbrella Review.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Vascular depression in Black Americans: A systematic review of the construct and its cognitive, functional, and psychosocial correlates.The Clinical neuropsychologist · 2022Pooled it
- Cognitive Gains of Aerobic Exercise in Patients With Ischemic Cerebrovascular Disorder: A Systematic Review and Meta-Analysis.Frontiers in cell and developmental biology · 2020Pooled it
- Associations of plasma biomarkers of Alzheimer's disease pathology with modifiable risk factors and cognitive and functional outcomes: evidence from cross-sectional prediction and latent path analyses in the Bio-Hermes-001 cohort.Alzheimer's research & therapy · 2026Article
- Effects of moderate- and high-intensity exercise on behavior and oxidative damage in male and female rats subjected to early life stress.Experimental brain research · 2026Article
- Triglyceride-glucose index, genetic predisposition, and incident depression: a prospective cohort study from the UK Biobank.Psychological medicine · 2026Article
- Microvascular Failure in the Aging Brain: Converging Pathways of Oxidative Stress, Inflammation, and Endothelial Decline.Biomedicines · 2026Review
- Microglial Activation in Cerebrovascular Accidents and the Manifestation of Major Depressive Disorder: A Comprehensive Review.Brain sciences · 2025Review
- METS-IR and SII as mediators in the association between smoking and depressive symptoms: insights from NHANES (2005-2018).BMC psychiatry · 2025Article
- Gut microbiota distinguishes aging hispanics with Alzheimer's disease: associations with cognitive impairment and severity.Scientific reports · 2025Article
- Association between triglyceride glucose index and depression in polycystic ovary syndrome.BMC endocrine disorders · 2025Article
- Physical Activity and Depression in Breast Cancer Patients: Mechanisms and Therapeutic Potential.Current oncology (Toronto, Ont.) · 2025Review
- Superoxide dismutase is associated with cerebral small vessel disease burden and vascular mild cognitive impairment in elderly patients.Frontiers in neuroscience · 2025Article
- The association of triglyceride glucose waist-to-height ratio index with depression in United States adults.Frontiers in nutrition · 2025Article
- Article
- Aerobic Exercise Improves Cognitive Recovery in Mice with Chronic Cerebral Hypoperfusion by Modulating the Annexin-A1-MAPK Axis and Astrocyte Polarization.Aging and disease · 2024Article
- The association between lymphocyte to high-density lipoprotein ratio and depression: Data from NHANES 2015-2018.Brain and behavior · 2024Article
- The role of exercise-related FNDC5/irisin in depression.Frontiers in pharmacology · 2024Review
- Alkaline phosphatase is associated with vascular depression in patients with severe white matter hyperintensities.Frontiers in neuroscience · 2024Article
- Chrysin Attenuates Oxidative Stress to Alleviate Sevoflurane-Induced Cognitive Impairments in Aged Rats.Psychiatry investigation · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress- (OS-) related endothelial damage is involved in the occurrence and progression of several disorders, such as vascular depression and dementia. It has been reported that moderate, aerobic, physical exercise could reduce OS and inflammation, thus limiting the cardiovascular risk factors while improving endothelial homeostasis, mood, and cognition. In this review, we will discuss about the role of OS and OS-related endothelial damage in vascular depression and vascular cognitive impairment. Then, we will comment on the effects of physical exercise on both disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.