Evidence map›Paper›PMID 31929816›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2019

Screening and Identification of Molecular Targets Involved in Preventing Gastric Precancerous Lesions in Chronic Atrophic Gastritis by Qilianshupi Decoction.

Yameng Zhang, Chao Li, Shanmei Sun, Zhiqun Cao, Jian Chen, Hongjie Xiang, Lucheng Song

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Clinical efficacy ofAmerican journal of translational research · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yameng ZhangThe First Affiliated Hospital of Shandong First Medical University, Jinan 250355, China.ORCID https://orcid.org/0000-0002-5511-3526
Chao LiShandong University of Traditional Chinese Medicine, Jinan 250355, China.
Shanmei SunThe First Affiliated Hospital of Shandong First Medical University, Jinan 250355, China.
Zhiqun CaoDigestive Department, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250000, China.
Jian ChenJinan Central Hospital Affiliated to Shandong University, Jinan 250000, China.
Hongjie XiangThe First Affiliated Hospital of Shandong First Medical University, Jinan 250355, China.ORCID https://orcid.org/0000-0002-7211-8214
Lucheng SongThe First Affiliated Hospital of Shandong First Medical University, Jinan 250355, China.ORCID https://orcid.org/0000-0003-2403-5526
Shandong First Medical University · CNShandong University of Traditional Chinese Medicine · CNShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic atrophic gastritis (CAG) is a common and possibly precancerous digestive tract disease. Development of drugs with effect of preventing precancerous lesions draws the eyes of global researchers. Qilianshupi decoction (QLSP) is a Traditional Chinese Medicine (TCM) that is commonly used to treat CAG, but few studies have explored the mechanism of QLSP on treating CAG. This study investigated the molecular targets of the component herbs of QLSP in preventing precancerous lesions based on network pharmacology. Network pharmacology analysis revealed that the 6 herbs regulated multiple CAG-related genes, among which the most important were cancer-related pathway (apoptosis, p53, and VEGF) and epithelial cell signaling in

Identifiers

PMID31929816
PMCPMC6942842
OpenAlexW2998415809

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.