ArticlePloS one2020
TaWAK6 encoding wall-associated kinase is involved in wheat resistance to leaf rust similar to adult plant resistance.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 85 citations in OpenAlex.
- ZmWAKL21 is a maize wall-associated kinase-like protein that interacts with AvrRppC and contributes to southern corn rust resistance.Cellular & molecular biology letters · 2026Article
- Wheat Plasma Membrane Receptors: Orchestrating Immunity and Bridging to Crop Improvement.Current issues in molecular biology · 2025Review
- TaWAKL8-2B, a wall-associated receptor-like kinase, mediates wheat rust resistance by linalool and ROS accumulation.Stress biology · 2025Article
- Transcriptional Dynamics of Receptor-Based Genes Reveal Immunity Hubs in Rice Response toInternational journal of molecular sciences · 2025Article
- Function of WAKs in Regulating Cell Wall Development and Responses to Abiotic Stress.Plants (Basel, Switzerland) · 2025Review
- Salicylic Acid Mediates Chitosan-Induced Immune Responses and Growth Enhancement in Barley.International journal of molecular sciences · 2024Article
- Identification of quantitative trait loci associated with leaf rust resistance in rye by precision mapping.BMC plant biology · 2024Article
- The ZmWAKL-ZmWIK-ZmBLK1-ZmRBOH4 module provides quantitative resistance to gray leaf spot in maize.Nature genetics · 2024Article
- Transcriptome analysis under pecan scab infection reveals the molecular mechanisms of the defense response in pecans.PloS one · 2024Article
- Genome-wide characterization of the wall-associated kinase-like (WAKL) family in sesame (Sesamum indicum) identifies a SiWAKL6 gene involved in resistance to Macrophomina Phaseolina.BMC plant biology · 2023Article
- Genome-Wide Association Study Reveals Novel Powdery Mildew Resistance Loci in Bread Wheat.Plants (Basel, Switzerland) · 2023Article
- Wall-associated kinase BrWAK1 confers resistance to downy mildew in Brassica rapa.Plant biotechnology journal · 2023Article
- Comparative genomics analysis of WAK/WAKL family in Rosaceae identify candidate WAKs involved in the resistance to Botrytis cinerea.BMC genomics · 2023Article
- Assessment of TunisianMicroorganisms · 2023Article
- The WAK-like protein RFO1 acts as a sensor of the pectin methylation status in Arabidopsis cell walls to modulate root growth and defense.Molecular plant · 2023Article
- Genome-Wide Analysis of thePlants (Basel, Switzerland) · 2023Article
- A Novel Wall-Associated Kinase TaWAK-5D600 Positively Participates in Defense against Sharp Eyespot andInternational journal of molecular sciences · 2023Article
- Whole-genome sequencing uncovers the structural and transcriptomic landscape of hexaploid wheat/Ambylopyrum muticum introgression lines.Plant biotechnology journal · 2023Article
- Characterization of theInternational journal of molecular sciences · 2022Article
- Harnessing genetic resistance to rusts in wheat and integrated rust management methods to develop more durable resistant cultivars.Frontiers in plant science · 2022Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In wheat, adult plant resistance (APR) to leaf rust (Puccinia triticina), is effective in restricting pathogen growth and provides durable resistance against a wide range of virulent forms of P. triticina. Despite the importance, there is limited knowledge on the molecular basis of this type of resistance. We isolated and characterized the wall-associated kinase encoding gene in wheat, and assigned it as TaWAK6. Localization of TaWAK6 homeologs in A and B wheat subgenomes was consistent with the presence of the gene's orthologs in T. urartu (AA) and T. dicoccoides (AABB) and with the absence of its orthologs in Aegilops tauschii (DD). Overexpression of TaWAK6 did not change the wheat phenotype, nor did it affect seedling resistance. However, the adult plants overexpressing TaWAK6 showed that important parameters of APR were significantly elevated. Infection types scored on the first (flag), second and third leaves indicated elevated resistance, which significantly correlated with expression of TaWAK6. Analysis of plant-pathogen interactions showed a lower number of uredinia and higher rates of necrosis at the infection sites and this was associated with smaller size of uredinia and a longer latent period. The results indicated a role of TaWAK6 in quantitative partial resistance similar to APR in wheat. It is proposed that TaWAK6, which is a non-arginine-aspartate (non-RD) kinase, represents a novel class of quantitative immune receptors in monocots.
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