Evidence map›Paper›PMID 31929538›Full record

ArticlePloS one2020

Trends of the prevalence and incidence of hypertrophic cardiomyopathy in Korea: A nationwide population-based cohort study.

Inki Moon, Seo-Young Lee, Hyung-Kwan Kim, Kyung-Do Han, Soongu Kwak, Minkwan Kim, Hyun-Jung Lee, In-Chang Hwang, Heesun Lee, Jun-Bean Park and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05645939 (Association of Obesity and Cardiovascular Outcomes in Patients With Hypertrophic Cardiomyopathy), which is not on this map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05645939 unknown statusnot on this mapstarted 2022, after this paper: background citation

Association of Obesity and Cardiovascular Outcomes in Patients With Hypertrophic Cardiomyopathy : a Korean Nationwide Cohort Study

Typeobservational_patient_registrySponsorAjou University School of MedicineRan2022 to 2024Enrolled30,000ConditionsObesity, Hypertrophic Cardiomyopathy, Cardiovascular MorbidityArmsDiasgnosis of hypertrophic cardiomyopathy
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Identification of recurrentCardiovascular diagnosis and therapy · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Hypertrophic cardiomyopathy: insights into pathophysiology and novel therapeutic strategies from clinical studies.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
  13. Article
  14. Article
  15. Current and Future of Heart Failure Care in Asia.International journal of heart failure · 2024
    Review
  16. Article
  17. Article
  18. Review
  19. High prevalence ofFrontiers in cardiovascular medicine · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Inki MoonDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Seo-Young LeeDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Hyung-Kwan KimDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.ORCID 0000-0001-7950-2131
Kyung-Do HanDepartment of Medical Statistics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Soongu KwakDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Minkwan KimDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.ORCID 0000-0002-4079-8219
Hyun-Jung LeeDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
In-Chang HwangDepartment of Cardiology, Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam, Gyeonggi, South Korea.
Heesun LeeDivision of Cardiology, Department of Internal Medicine, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.
Jun-Bean ParkDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.ORCID 0000-0003-4053-8713
Yeonyee E YoonDepartment of Cardiology, Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam, Gyeonggi, South Korea.
Yong-Jin KimDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
Goo-Yeong ChoDepartment of Cardiology, Cardiovascular Center, Seoul National University Bundang Hospital, Seongnam, Gyeonggi, South Korea.
Seoul National University Hospital · KRSeoul National University Bundang Hospital · KRCatholic University of Korea · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Temporal trends of the prevalence and incidence of hypertrophic cardiomyopathy (HCM) have not been well established in Asian populations. Using the Korean National Health Insurance Services database, we identified patients with a confirmed diagnosis of HCM between 2010 and 2016. The annual prevalence and incidence of HCM, and their clinical characteristics were investigated. The prevalence of HCM has increased from 0.016% (n = 6313) in 2010 to 0.031% (n = 13,035) in 2016. During a 7-year period, 13,229 patients were newly diagnosed with HCM. The incidence rate increased from 4.15 (per 100,000 person-years) in 2010 to 5.6 in 2016. The prevalence and incidence of HCM increased with age and peaked during the 70s, with male predominance in all age groups. Chest pain is the most frequent clinical presentation followed by shortness of breath and syncope. Hypertension and dyslipidemia were the two most common comorbidities. Heart failure and atrial fibrillation was diagnosed in about 1/3 and 1/4 of patients with HCM, respectively. The prevalence and incidence of HCM gradually increased from 2010 to 2016, possibly due to heightened recognition of the disease. Given the progressively high incidence of HCM with age and high prevalence of coexisting modifiable risk factors, continued efforts are required to increase awareness regarding HCM-related symptoms and potential complications.

Indexed as

AgedAtrial FibrillationCardiomyopathy, HypertrophicChest PainCohort StudiesComorbidityDatabases, FactualFemaleHeart FailureHumansIncidenceMaleMiddle AgedPrevalenceRepublic of KoreaRisk Factors

Identifiers

PMID31929538
PMCPMC6957184
OpenAlexW2998888622

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.