Evidence map›Paper›PMID 31929363›Full record

ReviewChinese medical journal2020

Recent progress in Helicobacter pylori treatment.

Yi Hu, Yin Zhu, Nong-Hua Lu

Abstract readReview
In one paragraph

Review in Chinese medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Minocycline in the eradication ofWorld journal of gastroenterology · 2024
    Pooled it
  3. Pooled it
  4. Vitamins andFrontiers in nutrition · 2021
    Pooled it
  5. Different dose of new generation proton pump inhibitors for the treatment ofInternational journal of immunopathology and pharmacology
    Pooled it
  6. Trial
  7. [Molecular mechanisms of chronic gastric mucosal inflammation induced byZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Review
  8. Review
  9. Levofloxacin and Rifampin Resistance inAntibiotics (Basel, Switzerland) · 2026
    Article
  10. Barriers toBMJ open · 2026
    Article
  11. Eco-Friendly Synthesis and Characterization ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  12. Eradication ofIranian journal of microbiology · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Tegoprazan-Containing Versus Proton Pump Inhibitor-Containing Therapy for First-Line Eradication ofJGH open : an open access journal of gastroenterology and hepatology · 2025
    Review
  18. The efficacy and safety of Vonoprazan and Tegoprazan inTherapeutic advances in gastroenterology · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yi HuDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China.
Yin Zhu
Nong-Hua Lu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The main challenge in the field of Helicobacter pylori (H. pylori) infection is antibiotic resistance, which influences the efficacy of eradication regimens. Bismuth-containing quadruple therapy has been confirmed as an effective regimen for eradicating H. pylori, especially in strains with antibiotic resistance. High-dose proton-pump inhibitor-amoxicillin dual therapy could decrease the use of unnecessary antibiotics, which is a promising alternative approach. Adjuvant therapy (specific probiotic or vitamin) also showed good results, although more evidence is needed. Novel anti-H. pylori drugs are needed, and the establishment of the H. pylori database is an effective way to acknowledge the real-time information of H. pylori management. This review provides the recent progress of H. pylori treatment, and further studies are needed to address the role of different regimens in improving H. pylori eradication rate, especially in strains with antibiotics resistance.

Indexed as

AmoxicillinAnti-Bacterial AgentsBismuthDrug Therapy, CombinationHelicobacter InfectionsHelicobacter pyloriHumansMetronidazoleProbioticsProton Pump InhibitorsPyrrolesSulfonamidesVitamins1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamineAmoxicillinAnti-Bacterial AgentsBismuthMetronidazoleProton Pump InhibitorsPyrrolesSulfonamidesVitamins

Identifiers

PMID31929363
PMCPMC7004604

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.