Evidence map›Paper›PMID 31929112›Full record

ArticleAging2020

Association between SOD2 V16A variant and urological cancer risk.

Li-Feng Zhang, Kai Xu, Bo-Wen Tang, Wei Zhang, Wei Yuan, Chuang Yue, Li Shi, Yuan-Yuan Mi, Li Zuo, Li-Jie Zhu

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  9. Analytical Validation ofMethods and protocols · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Li-Feng ZhangDepartment of Urology, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
Kai XuDepartment of Urology, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
Bo-Wen TangDepartment of Urology, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
Wei ZhangDepartment of Oncology, Taizhou People's Hospital, Taizhou 225300, China.
Wei YuanDepartment of Cardiology, Taizhou People's Hospital, Taizhou 225300, China.
Chuang YueDepartment of Urology, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
Li ShiDepartment of Urology, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
Yuan-Yuan MiDepartment of Urology, Affiliated Hospital of Jiangnan University, Wuxi 214000, China.
Li ZuoDepartment of Urology, The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou 213003, China.
Li-Jie ZhuDepartment of Urology, Affiliated Hospital of Jiangnan University, Wuxi 214000, China.
Changzhou No.2 People's Hospital · CNNanjing Medical University · CNJiangnan University · CNNantong University · CNTaizhou People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe correlation between superoxide dismutase 2 (SOD2) V16A variant and urological cancer susceptibility has been widely studied, however, with divergent results.

resultsTotally, 9,910 cancer patients and 11,239 control subjects were enrolled. V16A variant is associated with an increased susceptibility to urological cancer (A-allele vs. V-allele: OR = 1.06, 95% CI = 1.00 - 1.13,

conclusionsThe SOD2 V16A variant may be associated with increased urological cancer susceptibility, especially for prostate cancer.

methodsA pooled analysis utilizing odds ratios (ORs),

Indexed as

Genetic Predisposition to DiseaseGenetic VariationAdultAgedAllelesBiomarkers, TumorComputational BiologyDNA MethylationEpistasis, GeneticFemaleGene Expression ProfilingGene FrequencyGenetic Association StudiesGenotypeHumansImmunohistochemistryBiomarkers, TumorSuperoxide DismutaseSuperoxide Dismutase 2analysisin silicoSOD2urological cancervariant

Identifiers

PMID31929112
PMCPMC6977677
OpenAlexW2999295200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.