ArticleCurrent biology : CB2020
Heterogeneous Temporal Contrast Adaptation in Drosophila Direction-Selective Circuits.
Article in Current biology : CB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 51 citations in OpenAlex.
- Broken time-reversal symmetry in visual motion detection.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- A recurrent neural circuit in Drosophila temporally sharpens visual inputs.Current biology : CB · 2025Article
- Adaptation to visual sparsity enhances responses to isolated stimuli.Current biology : CB · 2024Article
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- Neural pathways and computations that achieve stable contrast processing tuned to natural scenes.Nature communications · 2024Article
- Optimization in Visual Motion Estimation.Annual review of vision science · 2024Review
- Broken time reversal symmetry in visual motion detection.bioRxiv : the preprint server for biology · 2024Article
- A recurrent neural circuit inbioRxiv : the preprint server for biology · 2024Article
- An open platform for visual stimulation of insects.PloS one · 2024Article
- Neural mechanisms to incorporate visual counterevidence in self-movement estimation.Current biology : CB · 2023Article
- Direct comparison reveals algorithmic similarities in fly and mouse visual motion detection.iScience · 2023Article
- Long-timescale anti-directional rotation ineLife · 2023Article
- Neural mechanisms to incorporate visual counterevidence in self motion estimation.bioRxiv : the preprint server for biology · 2023Article
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- Long timescale anti-directional rotation in Drosophila optomotor behavior.bioRxiv : the preprint server for biology · 2023Article
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- Contrast independent biologically inspired translational optic flow estimation.Biological cybernetics · 2022Article
- Excitatory and inhibitory neural dynamics jointly tune motion detection.Current biology : CB · 2022Article
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5 authors at 3 institutions in 1 country.
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Abstract
In visual systems, neurons adapt both to the mean light level and to the range of light levels, or the contrast. Contrast adaptation has been studied extensively, but it remains unclear how it is distributed among neurons in connected circuits, and how early adaptation affects subsequent computations. Here, we investigated temporal contrast adaptation in neurons across Drosophila's visual motion circuitry. Several ON-pathway neurons showed strong adaptation to changes in contrast over time. One of these neurons, Mi1, showed almost complete adaptation on fast timescales, and experiments ruled out several potential mechanisms for its adaptive properties. When contrast adaptation reduced the gain in ON-pathway cells, it was accompanied by decreased motion responses in downstream direction-selective cells. Simulations show that contrast adaptation can substantially improve motion estimates in natural scenes. The benefits are larger for ON-pathway adaptation, which helps explain the heterogeneous distribution of contrast adaptation in these circuits.
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