Evidence map›Paper›PMID 31928422›Full record

ArticleCancer biotherapy & radiopharmaceuticals2020

The Monoclonal Antibody NEO-201 Enhances Natural Killer Cell Cytotoxicity Against Tumor Cells Through Blockade of the Inhibitory CEACAM5/CEACAM1 Immune Checkpoint Pathway.

Massimo Fantini, Justin M David, Christina M Annunziata, Maria Pia Morelli, Phillip M Arlen, Kwong Y Tsang

Open access · bronzeAbstract read
In one paragraph

Article in Cancer biotherapy & radiopharmaceuticals, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. The Biological Significance of Trogocytosis.Results and problems in cell differentiation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Massimo FantiniPrecision Biologics, Inc., Bethesda, Maryland.
Justin M DavidPrecision Biologics, Inc., Bethesda, Maryland.
Christina M AnnunziataWomen's Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Maria Pia MorelliWomen's Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Phillip M ArlenPrecision Biologics, Inc., Bethesda, Maryland.
Kwong Y TsangPrecision Biologics, Inc., Bethesda, Maryland.
Precision BioLogic (Canada) · CA

Funding

Immune cell control of ovarian cancerZIABC011775 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ANNUNZIATA, CHRISTINA · 2017 to 2023
$3.6M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntibodies, MonoclonalCarcinoembryonic AntigenCarcinomaCell Line, TumorGPI-Linked ProteinsHumansKiller Cells, NaturalMiceAntibodies, MonoclonalCarcinoembryonic AntigenCEACAM5 protein, humanGPI-Linked ProteinsCEACAM5immune checkpoint pathwaymonoclonal antibodynatural killer cellsNEO-201NK cell cytotoxicity

Identifiers

PMID31928422
PMCPMC7360111
OpenAlexW2999126010

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.