ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2020
Uncoupling of sarcoendoplasmic reticulum calcium ATPase pump activity by sarcolipin as the basis for muscle non-shivering thermogenesis.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Gut Microbial Community and Host Thermoregulation in Small Mammals.Frontiers in physiology · 2022Pooled it
- Limb restraint induces a rapid and profound decrease in core body temperature associated with the stress response in mice.PNAS nexus · 2026Article
- Effects of electromyostimulation on sarcolipin and CaBiochemistry and biophysics reports · 2026Article
- Transcriptome profile of Min pig muscle response to cold stress.Veterinary and animal science · 2026Article
- Characterization of Genes Related to Intramuscular Fat Deposition in Muscles of Piglets Under Cold Exposure by Whole Transcriptome Sequencing.Current issues in molecular biology · 2026Article
- Melatonin promotes skeletal muscle mitochondria-associated endoplasmic reticulum membrane contacts and restores organellar membrane integrity and phospholipid composition in Zücker diabetic fatty rats of both sexes.Cell communication and signaling : CCS · 2026Article
- Body Temperature Regulation in the Rat by Muscle Tone.Acta physiologica (Oxford, England) · 2026Article
- Dysferlin and the Regulation of CaCells · 2025Review
- Role of Dyadic Proteins in Proper Heart Function and Disease.International journal of molecular sciences · 2025Review
- Molecular mechanisms of UCP1-independent thermogenesis: the role of futile cycles in energy dissipation.Journal of physiology and biochemistry · 2025Review
- Genetic and Epigenetic Adaptation Mechanisms of Sheep Under Multi-Environmental Stress Environment.International journal of molecular sciences · 2025Review
- Integrative paleophysiology of the metriorhynchoid Pelagosaurus typus (Pseudosuchia, Thalattosuchia).Anatomical record (Hoboken, N.J. : 2007) · 2025Article
- Natural bioactive compounds and their mechanisms of action in the management of obesity: a narrative review.Frontiers in nutrition · 2025Review
- Chronic cold exposure causes left ventricular hypertrophy that appears to be physiological.The Journal of experimental biology · 2024Article
- Adaptive Induction of Nonshivering Thermogenesis in Muscle Rather Than Brown Fat Could Counteract Obesity.Physiological research · 2024Review
- Adipose Tissue Dysfunction Related to Climate Change and Air Pollution: Understanding the Metabolic Consequences.International journal of molecular sciences · 2024Review
- Mild Hyperthermia-Induced Thermogenesis in the Endoplasmic Reticulum Defines Stress Response Mechanisms.Cells · 2024Article
- Article
- On the origins of endothermy in amniotes.iScience · 2024Article
- Summer fades, deer change: Photoperiodic control of cellular seasonal acclimatization of skeletal muscle.iScience · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Thermogenesis in endotherms relies on both shivering and non-shivering thermogenesis (NST). The role of brown adipose tissue (BAT) in NST is well recognized, but the role of muscle-based NST has been contested. However, recent studies have provided substantial evidence for the importance of muscle-based NST in mammals. This review focuses primarily on the role of sarcoplasmic reticulum (SR) Ca
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.