Evidence map›Paper›PMID 31928144›Full record

ArticleRNA biology2020

HuR stabilizes

Quan Zhao, Chen Li, Meng Yu, Yimin Sun, Jian Wang, Lixiang Ma, Xiaoli Sun, Boxun Lu

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Quan ZhaoNeurology Department at Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Biomedical Sciences, School of Life Sciences, Fudan University, Shanghai, China.
Chen LiNeurology Department at Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Biomedical Sciences, School of Life Sciences, Fudan University, Shanghai, China.
Meng YuNeurology Department at Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Biomedical Sciences, School of Life Sciences, Fudan University, Shanghai, China.
Yimin SunNeurology Department at Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Biomedical Sciences, School of Life Sciences, Fudan University, Shanghai, China.
Jian WangNeurology Department at Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Biomedical Sciences, School of Life Sciences, Fudan University, Shanghai, China.ORCID 0000-0002-2748-395X
Lixiang MaDepartment of Anatomy, Histology and Embryology, Shanghai Basic Medical College, Fudan University, Shanghai, China.
Xiaoli SunNeurology Department at Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Biomedical Sciences, School of Life Sciences, Fudan University, Shanghai, China.
Boxun LuNeurology Department at Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Biomedical Sciences, School of Life Sciences, Fudan University, Shanghai, China.ORCID 0000-0002-1675-9340
Fudan University · CNShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huntington's Disease (HD) is a monogenetic neurodegenerative disorder mainly caused by the cytotoxicity of the mutant HTT protein (mHTT) encoded by the mutant

Indexed as

Mutation3' Untranslated RegionsAnimalsBinding SitesCell LineCRISPR-Cas SystemsELAV-Like Protein 1ExonsFeedback, PhysiologicalGene Knockdown TechniquesHEK293 CellsHumansHuntingtin ProteinHuntington DiseaseMiceMitogen-Activated Protein Kinase 113' Untranslated RegionsELAVL1 protein, humanELAV-Like Protein 1HTT protein, humanHuntingtin ProteinMitogen-Activated Protein Kinase 11CAG repeatsHuntington’s diseaseMAPKneurodegenerationp38polyglutamineRNA binding protein

Identifiers

PMID31928144
PMCPMC7237150
OpenAlexW2999931994

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.