ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2020
Racial discrimination and telomere shortening among African Americans: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.
Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed, 4 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Racial/Ethnic Discrimination and Cardiometabolic Diseases: A Systematic Review.Journal of racial and ethnic health disparities · 2024Pooled it
- Social support and telomere length: a meta-analysis.Journal of behavioral medicine · 2023Pooled it
- A systematic review and meta-analysis of the Everyday Discrimination Scale and biomarker outcomes.Psychoneuroendocrinology · 2022Pooled it
- Perceived Discrimination and Immunological Aging: A Systematic Review of Cellular and Molecular Markers.Biopsychosocial science and medicinePooled it
- Mitigating the health effects of systemic racism: Evaluation of the Race-Based Stress and Trauma Empowerment intervention.Contemporary clinical trials · 2023Trial
- Impact of racial discrimination in education and other adverse childhood experiences on black students' mental health and wellbeing: an interpretative phenomenological analysis study.International journal of qualitative studies on health and well-being · 2025Article
- Lifetime trauma exposure and accelerated epigenetic aging among midlife women.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025Article
- Health Disparities at the Intersection of Racism, Social Determinants of Health, and Downstream Biological Pathways.International journal of environmental research and public health · 2025Review
- The role of optimism, connectedness, and neighborhood collective efficacy as moderators of harsh parenting on telomere length.Psychoneuroendocrinology · 2025Article
- Discrepancies in Cardiovascular Disease Risk Perception Among African American Emerging Adults.Nursing (Auckland, N.Z.) · 2025Article
- Causal association between telomere length and female reproductive endocrine diseases: a univariable and multivariable Mendelian randomization analysis.Journal of ovarian research · 2024Article
- Piloting a Measure of Segregation at the Census Tract Level: Associations with Place and Racial/Ethnic Disparities in Life Expectancy.International journal of environmental research and public health · 2024Article
- Everyday Discrimination Is Associated With Higher Odds of Hospitalizations Among Older African Americans.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Profiles of cardiometabolic risk and acculturation indicators among South Asians in the US: latent class analysis of the MASALA study.Frontiers in public health · 2024Article
- The Stress Phenotyping Framework: A multidisciplinary biobehavioral approach for assessing and therapeutically targeting maladaptive stress physiology.Stress (Amsterdam, Netherlands) · 2024Review
- Discrimination and bladder health among women in the CARDIA cohort study: Life course and intersectionality perspectives.Social science & medicine (1982) · 2024Article
- The relationship between greenspace exposure and telomere length in the National Health and Nutrition Examination Survey.The Science of the total environment · 2023Article
- Measures of Aging Biology in Saliva and Blood as Novel Biomarkers for Stroke and Heart Disease in Older Adults.Neurology · 2023Article
- The Water Surrounding the Iceberg: Cultural Racism and Health Inequities.The Milbank quarterly · 2023Article
- Article
Corrections and comments
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Authors and funding
13 authors at 9 institutions in 2 countries.
Funding
Abstract
objectiveTelomeres are protective sequences of DNA capping the ends of chromosomes that shorten over time. Leukocyte telomere length (LTL) is posited to reflect the replicative history of cells and general systemic aging of the organism. Chronic stress exposure leads to accelerated LTL shortening, which has been linked to increased susceptibility to and faster progression of aging-related diseases. This study examined longitudinal associations between LTL and experiences of racial discrimination, a qualitatively unique source of minority psychosocial stress, among African Americans.
methodData are from 391 African Americans in the Coronary Artery Risk Development in Young Adults (CARDIA) Telomere Ancillary Study. We examined the number of domains in which racial discrimination was experienced in relation to LTL collected in Years 15 and 25 (Y15: 2000/2001; Y25: 2010/2011). Multivariable linear regression examined if racial discrimination was associated with LTL. Latent change score analysis (LCS) examined changes in racial discrimination and LTL in relation to one another.
resultsControlling for racial discrimination at Y15, multivariable linear regression analyses indicated that racial discrimination at Y25 was significantly associated with LTL at Y25. This relationship remained robust after adjusting for LTL at Y15 (b = -.019,
conclusionsThis study adds to evidence that racial discrimination contributes to accelerated physiologic weathering and health declines among African Americans through its impact on biological systems, including via its effects on telomere attrition. (PsycINFO Database Record (c) 2020 APA, all rights reserved).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.