ArticleMarine biotechnology (New York, N.Y.)2020
Identification of Candidate Growth-Related SNPs and Genes Using GWAS in Brown-Marbled Grouper (Epinephelus fuscoguttatus).
Article in Marine biotechnology (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 72 citations in OpenAlex.
- Genome-Wide Association Analysis for Growth-Related Traits in Indoor- and Outdoor-Cultured Juvenile Grass Carp (Animals : an open access journal from MDPI · 2026Article
- Establishment and characterization of a continuous cell line from eye of the brown-marbled grouper (Epinephelus fuscoguttatus) for virological studies.In vitro cellular & developmental biology. Animal · 2026Article
- Whole-Genome Resequencing-Based GWAS Reveals Major-Effect Loci and Candidate Genes for Growth Traits in Topmouth Culter (Animals : an open access journal from MDPI · 2026Article
- Genome-Wide Association Study SuggestsCurrent issues in molecular biology · 2026Article
- Identification of Genes Related to Rapid Growth of Giant Grouper (Animals : an open access journal from MDPI · 2025Article
- Construction of a Core Germplasm and Identification of Candidate SNPs Associated with Growth Performance of Epinephelus tukula by Whole-Genome Resequencing.Marine biotechnology (New York, N.Y.) · 2025Article
- Genome-Wide Association Study and RNA-Seq Analysis Uncover Candidate Genes Controlling Growth Traits in Red Tilapia (International journal of molecular sciences · 2025Article
- Genome-Wide Association Analysis and Genomic Selection for Growth Traits in Grass Carp (Animals : an open access journal from MDPI · 2025Article
- Genome-Wide Association Study for Weight-Related Traits inAnimals : an open access journal from MDPI · 2025Article
- Genome-wide association study (GWAS) provides insights into the genomic basis of reproduction-related traits in Chouardia litardierei (Asparagaceae).BMC plant biology · 2025Article
- Deciphering the population structure and genetic basis of growth traits from whole-genome resequencing of the leopard coral grouper (Zoological research · 2024Article
- Assembly of Genome and Resequencing Provide Insights into Genetic Differentiation between Parents of Hulong Hybrid Grouper (International journal of molecular sciences · 2023Article
- Unraveling the complex genetic basis of growth in New Zealand silver trevally (Pseudocaranx georgianus).G3 (Bethesda, Md.) · 2022Article
- Linkage mapping and QTL analysis of growth traits in Rhopilema esculentum.Scientific reports · 2022Article
- Bioinformatics Approach to Mitigate Mislabeling in EU Seafood Market and Protect Consumer Health.International journal of environmental research and public health · 2021Article
- Prognostic Value of Circadian Rhythm of Brain Temperature in Traumatic Brain Injury.Journal of personalized medicine · 2021Article
- Article
- The Polymorphism of LvMMD2 and Its Association with Growth Traits in Litopenaeus vannamei.Marine biotechnology (New York, N.Y.) · 2020Article
- Whole-genome sequencing of leopard coral grouper (Zoological research · 2020Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
Brown-marbled grouper, Epinephelus fuscoguttatus, is not only an important commercial fish species, but also an important crossbreeding parent in grouper industry. Improvement of growth traits of this species contributes to the development of grouper breeding. Currently, the development of molecular marker associated with growth of brown-marbled grouper is rare. Thus, we performed the first genome-wide association study (GWAS) for five growth traits in 172 brown-marbled groupers with 43,688 SNPs detected by ddRAD-seq. We identified a total of 5 significant and 18 suggestive QTLs located in multiple chromosomes associated with growth traits. In the 20 kb window of the significant SNPs and suggestive SNPs, 5 and 14 potential candidate genes affecting growth were detected, respectively. Five potential candidate genes near the significantly associated SNPs were selected for expression analysis. Among of which, bmp2k, wasf1, and acyp2 involved in bone development, maintenance of mitochondrion structure, and metabolism were differentially expressed. Interestingly, the SNP 23:29601315 located in the intron of bmp2k was significantly associated with body weight, body length, body height, and body thickness and suggestively associated with total length. We verified the locus using another new group including 123 individuals. The results showed that individuals with CC genotype have better growth traits comparing other individuals. Our findings not only contribute to understanding the molecular mechanism of growth regulation, but also promote the advance of marker-assisted selection in brown-marbled grouper.
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