Evidence map›Paper›PMID 31927513›Full record

ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2020

UTE-SPECIAL for3D localization at an echo time of 4 ms on a clinical 3 T scanner.

Karl Landheer, Ralph Noeske, Michael Garwood, Christoph Juchem

Abstract read
In one paragraph

Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Karl LandheerBiomedical Engineering, Columbia University Fu Foundation School of Engineering and Applied Science, New York, NY, United States. Electronic address: kl2968@columbia.edu.
Ralph NoeskeGE Healthcare, Berlin, Germany.
Michael GarwoodCenter for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, MN, United States.
Christoph JuchemBiomedical Engineering, Columbia University Fu Foundation School of Engineering and Applied Science, New York, NY, United States; Radiology, Columbia University College of Physicians and Surgeons, New York, NY, United States.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
TRD4 - Ultrahigh Field Engineering and SafetyP41EB027061 · NIBIB · UNIVERSITY OF MINNESOTA · PI Gregory John Metzger · 2019 to 2026
$11.7M
NCATS NIH HHS UL1 TR001863NIBIB NIH HHS P41 EB027061
6 · The paper itself

Abstract

Reducing the echo time of magnetic resonance spectroscopy experiments is appealing because it increases the available signal and reduces J-evolution of coupled metabolites. In this manuscript a novel sequence, referred to as Ultrashort echo TimE, SPin ECho, full Intensity Acquired Localized (UTE-SPECIAL), is described which is able to achieve ultrashort echo times (4 ms) on a standard clinical 3 T MR system while recovering the entirety of the available magnetization. UTE-SPECIAL obtains full 3D spatial localization through a 2D adiabatic inversion pulse which is cycled "on" and "off" every other repetition, in combination with a slice-selective excitation pulse. In addition to an ultrashort echo time, UTE-SPECIAL has negligible chemical shift displacement artefact and, because it uses no slice-selective refocusing pulse, has no signal cancellation at the borders for J-coupled metabolites. Spectra with an ultrashort echo time of 4 ms are demonstrated in vivo at 3 T, as well as J-resolved spectra obtained in a phantom and a healthy volunteer.

Indexed as

AdultArtifactsComputer SimulationHealthy VolunteersHumansImage Processing, Computer-AssistedImaging, Three-DimensionalMacromolecular SubstancesMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleParietal LobePhantoms, ImagingReproducibility of ResultsMacromolecular SubstancesIn vivo magnetic resonance spectroscopyJ-couplingSPECIALUltrashort TE MRS

Identifiers

PMID31927513
PMCPMC7045707

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.