Evidence map›Paper›PMID 31926877›Full record

ArticleResearch in social & administrative pharmacy : RSAP2020

Prevalence and factors associated with potentially inappropriate medication use in older medicare beneficiaries with cancer.

Xue Feng, Gerald M Higa, Fnu Safarudin, Usha Sambamoorthi, Jongwha Chang

Open access · greenAbstract read
In one paragraph

Article in Research in social & administrative pharmacy : RSAP, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Use of Potentially Inappropriate Medications in Older Allogeneic Hematopoietic Cell Transplantation Recipients.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Xue FengDepartment of Pharmaceutical Systems and Policy, West Virginia University, School of Pharmacy, WV, USA.
Gerald M HigaDepartment of Clinical Pharmacy, West Virginia University, School of Pharmacy, WV, USA. Electronic address: ghiga@hsc.wvu.edu.
Fnu SafarudinDepartment of Pharmaceutical Systems and Policy, West Virginia University, School of Pharmacy, WV, USA; Department of Pharmacy, School of Mathematics and Natural Sciences, Tadulako University-Palu, Central Sulawesi, Indonesia.
Usha SambamoorthiDepartment of Pharmaceutical Systems and Policy, West Virginia University, School of Pharmacy, WV, USA.
Jongwha ChangDepartment of Pharmacy Practice, The University of Texas, School of Pharmacy, El Paso, TX, USA.
West Virginia University · USThe University of Texas at El Paso · US

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Laura F. Gibson · 2012 to 2026
$81.0M
NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

objectiveTo assess the factors related to potentially inappropriate medication (PIM) use in elderly patients with cancer, as well as to compare the PIM prevalence in older adults with and without cancer.

methodsData from the Surveillance, Epidemiology, and End Results-Medicare-linked base (2009-2011) were accessed to conduct a retrospective study comparing patients with cancers of the breast, colon/rectum, and prostate against a matched population of subjects without cancer. PIM use was defined based on the 2015 Beers Criteria and was quantified using prescription claims. Multivariable logistic regression models were used to assess the associations between the patients' characteristics, clinical factors, and PIM use in patients with cancer based on Beers criteria. Propensity score matching was applied to compare use of PIM in patients with versus without cancer.

resultsPIM usage rates in patients with colorectal and breast cancers were significantly higher than non-cancer-bearing adults; the difference in PIM usage rate was not significantly different in the prostate cancer-matched cohort. The prevalence of inappropriate medication use in the three types of cancers evaluated was directly correlated with number of medications prescribed, treatment with chemotherapy, and co-morbid medical problems.

conclusionPatients diagnosed with cancer were more likely to use PIM compared with their non-cancer counterparts. The updated Beers criteria has the potential to serve as an important tool in geriatric oncology practice but it may still need to take into consideration different cancer types and their respective treatments.

Indexed as

NeoplasmsPotentially Inappropriate Medication ListAgedFemaleHumansInappropriate PrescribingMaleMedicarePrevalenceRetrospective StudiesUnited States

Identifiers

PMID31926877
PMCPMC7418487
OpenAlexW2997227043

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.