Evidence map›Paper›PMID 31926750›Full record

ArticleUltrasound in medicine & biology2020

The Stacked-Ellipse Algorithm: An Ultrasound-Based 3-D Uterine Segmentation Tool for Enabling Adaptive Radiotherapy for Uterine Cervix Cancer.

Sarah A Mason, Ingrid M White, Susan Lalondrelle, Jeffrey C Bamber, Emma J Harris

Abstract read
In one paragraph

Article in Ultrasound in medicine & biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sarah A MasonJoint Department of Physics, Institute of Cancer Research, London, United Kingdom.
Ingrid M WhiteRadiotherapy Department, Royal Marsden NHS Foundation Trust, London, United Kingdom.
Susan LalondrelleRadiotherapy Department, Royal Marsden NHS Foundation Trust, London, United Kingdom.
Jeffrey C BamberJoint Department of Physics, Institute of Cancer Research, London, United Kingdom.
Emma J HarrisJoint Department of Physics, Institute of Cancer Research, London, United Kingdom. Electronic address: emma.harris@icr.ac.uk.

Funding

Cancer Research UK 19727Cancer Research UK 23557Cancer Research UK 28284
6 · The paper itself

Abstract

The stacked-ellipse (SE) algorithm was developed to rapidly segment the uterus on 3-D ultrasound (US) for the purpose of enabling US-guided adaptive radiotherapy (RT) for uterine cervix cancer patients. The algorithm was initialised manually on a single sagittal slice to provide a series of elliptical initialisation contours in semi-axial planes along the uterus. The elliptical initialisation contours were deformed according to US features such that they conformed to the uterine boundary. The uterus of 15 patients was scanned with 3-D US using the Clarity System (Elekta Ltd.) at multiple days during RT and manually contoured (n = 49 images and corresponding contours). The median (interquartile range) Dice similarity coefficient and mean surface-to-surface-distance between the SE algorithm and manual contours were 0.80 (0.03) and 3.3 (0.2) mm, respectively, which are within the ranges of reported inter-observer contouring variabilities. The SE algorithm could be implemented in adaptive RT to precisely segment the uterus on 3-D US.

Indexed as

AdultAgedAlgorithmsFemaleHumansImaging, Three-DimensionalMiddle AgedUltrasonography, InterventionalUterine Cervical NeoplasmsUterus3-D ultrasoundImage-guided radiotherapySegmentationUltrasound-guided radiotherapyUterine cervix cancerUterus

Identifiers

PMID31926750
PMCPMC7043010

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.