ArticleLipids in health and disease2020
Low-density lipoprotein cholesterol goal attainment rates in high-risk patients with cardiovascular diseases and diabetes mellitus in Korea: a retrospective cohort study.
Article in Lipids in health and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Goal Attainment Rate in Secondary Prevention in Taiwan - A Chang Gung Research Database Study.Acta Cardiologica Sinica · 2026Article
- A multi-center, open-label, observational study to evaluate the efficacy and safety of LivaloZetFrontiers in endocrinology · 2026Observational
- Clinical burden and management gaps in atherosclerotic cardiovascular disease: A nationwide study of 687,212 patients in Taiwan, 2017-2023.International journal of cardiology. Heart & vasculature · 2025Article
- Innovative Lipid-Lowering Strategies: RNA-Based, Small Molecule, and Protein-Based Therapies.Endocrinology and metabolism (Seoul, Korea) · 2025Review
- Addressing Cardiovascular Diseases Challenges in South Korea: Strategies to Improve Outcomes.Korean circulation journal · 2025Review
- Interventions to improve adherence to lipid-lowering drugs: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Predicting low density lipoprotein cholesterol target attainment using machine learning in patients with coronary artery disease receiving moderate-dose statin therapy.Scientific reports · 2025Article
- Ten-year trends in lipid management among patients after myocardial infarction in South Korea.PloS one · 2024Observational
- Article
- Lipid-Lowering Efficacy of Combination Therapy With Moderate-Intensity Statin and Ezetimibe Versus High-Intensity Statin Monotherapy: A Randomized, Open-Label, Non-Inferiority Trial From Korea.Journal of lipid and atherosclerosis · 2023Article
- Low-Density Lipoprotein Cholesterol Levels Are Associated With Subsequent Stented-Territory Ischemic Stroke After Carotid Artery Stenting: A Single Center Retrospective Study.Journal of lipid and atherosclerosis · 2023Article
- Lipid Management in Korean People With Type 2 Diabetes Mellitus: Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement.Journal of lipid and atherosclerosis · 2023Review
- Lipid Management in Korean People with Type 2 Diabetes Mellitus: Korean Diabetes Association and Korean Society of Lipid and Atherosclerosis Consensus Statement.Diabetes & metabolism journal · 2023Review
- Physicians' misperceived cardiovascular risk and therapeutic inertia as determinants of low LDL-cholesterol targets achievement in diabetes.Cardiovascular diabetology · 2022Article
- Non-achievement of the Low-Density Lipoprotein Cholesterol Goal in Older Patients with Type 2 Diabetes Mellitus and a Very High Cardiovascular Disease Risk: A Multicenter Study in Vietnam.Annals of geriatric medicine and research · 2021Article
- Improving statin treatment strategies to reduce LDL-cholesterol: factors associated with targets' attainment in subjects with and without type 2 diabetes.Cardiovascular diabetology · 2021Article
- Current Status of Low-Density Lipoprotein Cholesterol Target Achievement in Patients with Type 2 Diabetes Mellitus in Korea Compared with Recent Guidelines.Diabetes & metabolism journal · 2021Article
- Prevalence, awareness, treatment, and control of dyslipidemia among diabetes mellitus patients and predictors of optimal dyslipidemia control: results from the Korea National Health and Nutrition Examination Survey.Lipids in health and disease · 2021Article
- Suboptimal management of dyslipidemia in everyday clinical practice: Alarming signals from real-world data.International journal of cardiology · 2020Article
- Identification and treatment of those most at risk for premature atherosclerotic cardiovascular disease: We just cannot seem to get it right.American journal of preventive cardiology · 2020Article
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5 authors.
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Abstract
backgroundReal-world evidence of low-density lipoprotein cholesterol (LDL-C) goal attainment rates for Asian patients is deficient. The objective of this study was to assess the status of dyslipidemia management, especially in high-risk patients with cardiovascular disease (CVD) including stroke and acute coronary syndrome (ACS).
methodsThis was a retrospective cohort study of 514,866 subjects from the National Health Insurance Service-National Health Screening Cohort database in Korea. Participants were followed up from 2002 to 2015. Subjects with a high-risk of CVD prior to LDL-C measurement and subjects who were newly-diagnosed for high-risk of CVD following LDL-C measurement were defined as known high-risk patients (n = 224,837) and newly defined high-risk patients (n = 127,559), respectively. Data were analyzed by disease status: stroke, ACS, coronary heart disease (CHD), peripheral artery disease (PAD), diabetes mellitus (DM) and atherosclerotic artery disease (AAD).
resultsOverall, less than 50% of patients in each disease category achieved LDL-C goals (LDL-C < 70 mg/dL in patients with stroke, ACS, CHD and PAD; and LDL-C < 100 mg/dL in patients with DM and AAD). Statin use was observed in relatively low proportions of subjects (21.5% [known high-risk], 34.4% [newly defined high-risk]). LDL-C goal attainment from 2009 to 2015 steadily increased but the goal-achiever proportion of newly defined high-risk patients with ACS remained reasonably constant (38.7% in 2009; 38.1% in 2015).
conclusionsLDL-C goal attainment rates in high-risk patients with CVD and DM in Korea demonstrate unmet medical needs. Proactive management is necessary to bridge the gap between the recommendations of clinical guidelines and actual clinical practice.
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