Evidence map›Paper›PMID 31925977›Full record

ArticleCancer science2020

Occupational sitting time and subsequent risk of cancer: The Japan Public Health Center-based Prospective Study.

Hikaru Ihira, Norie Sawada, Taiki Yamaji, Atsushi Goto, Taichi Shimazu, Hiroyuki Kikuchi, Shigeru Inoue, Manami Inoue, Motoki Iwasaki, Shoichiro Tsugane and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancer science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Hikaru IhiraEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.ORCID https://orcid.org/0000-0002-3910-5120
Norie SawadaEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.ORCID https://orcid.org/0000-0002-9936-1476
Taiki YamajiEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Atsushi GotoEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Taichi ShimazuEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Hiroyuki KikuchiDepartment of Preventive Medicine and Public Health, Tokyo Medical University, Tokyo, Japan.
Shigeru InoueDepartment of Preventive Medicine and Public Health, Tokyo Medical University, Tokyo, Japan.
Manami InoueEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.ORCID https://orcid.org/0000-0003-1276-2398
Motoki IwasakiEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.ORCID https://orcid.org/0000-0003-3319-4131
Shoichiro TsuganeEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Japan Public Health Center-based Prospective (JPHC) Study Group
Tokyo Medical University · JP

Funding

Grant in Aid for Cancer Research from the Ministry of Health, Labour and Welfare of JapanNational Cancer Centre Research and Development Fund 23-A-31 [toku] and 26-A-2
6 · The paper itself

Abstract

Although occupational sitting time has been associated with adverse health outcomes and mortality, the association with cancer incidence remains unknown. This study investigated the association between occupational sitting time and risk of total and site-specific cancer in a Japanese population. We evaluated 33 307 participants aged 50-79 years who responded to a questionnaire in 2000-2003 in the Japan Public Health Center-based Prospective Study and were followed until 2013. Participants were grouped by sitting time at work. Hazard ratio (HR) and 95% confidence interval (CI) of cancer incidence were calculated with adjustment for potential confounders including moderate-to-vigorous physical activity. During 10.2 years of follow-up, 3807 newly diagnosed cases of cancer were identified. Occupational sitting time was marginally associated with total cancer, with multivariable HRs for the ≥7 h/d vs 1 to <3 h/d category of 1.12 (95% CI, 0.99-1.26; P for trend = .071) in men, but not women. Among findings for cancers at specific sites, long occupational sitting time was associated with increased risk of pancreas cancer, with multivariable HRs for the ≥7 h/d vs 1 to <3 h/d category of 2.25 (95% CI, 1.17-4.34; P for trend = .021) in men, and lung cancer, with multivariable HRs for the ≥7 h/d vs 1 to <3 h/d category of 2.80 (95% CI, 1.33-5.90; P for trend = .013) in women. Extended sitting time at work was associated with an increased risk of pancreas cancer in men and lung cancer in women.

Indexed as

AgedExerciseFemaleHumansIncidenceJapanMaleMiddle AgedNeoplasmsProportional Hazards ModelsProspective StudiesPublic HealthRisk FactorsSitting PositionSurveys and QuestionnairesTime Factorscancer incidenceJapan Public Health Center-based Prospective Studyleisure-time physical activitysedentary behaviorsitting time

Identifiers

PMID31925977
PMCPMC7060463
OpenAlexW3000022605

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.