Evidence map›Paper›PMID 31925833›Full record

Trial reportTransplant international : official journal of the European Society for Organ Transplantation2020

A randomized, controlled, behavioral intervention to promote walking after abdominal organ transplantation: results from the LIFT study.

Marina Serper, Iwan Barankay, Sakshum Chadha, Justine Shults, Lauren S Jones, Kim M Olthoff, Peter P Reese

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Transplant international : official journal of the European Society for Organ Transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 6 pooled it
2.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 6 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Survivorship interventions after liver transplantation (LT): A systematic review of interventions targeting physical and psychosocial well-being after LT.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026
    Pooled it
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  4. Exercise interventions for adults after liver transplantation.The Cochrane database of systematic reviews · 2023
    Pooled it
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  7. Trial
  8. Review
  9. Article
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  15. Review
  16. Frailty in CKD and Transplantation.Kidney international reports · 2021
    Review
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  18. Review
  19. Introducing EL-FIT (Exercise and Liver FITness): A Smartphone App to Prehabilitate and Monitor Liver Transplant Candidates.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Marina SerperDivision of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Iwan BarankayThe Wharton School, University of Pennsylvania, Philadelphia, PA, USA.
Sakshum ChadhaRenal-Electrolyte and Hypertension Division, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Justine ShultsDepartment of Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, USA.
Lauren S JonesDivision of Gastroenterology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Kim M OlthoffDepartment of Surgery, Division of Transplant Surgery, University of Pennsylvania, Philadelphia, PA, USA.
Peter P ReeseLeonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA.
University of Pennsylvania · US

Funding

Developing technology-based approaches to improve access and quality of care in cirrhosisK23DK115897 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI SERPER, MARINA · 2018 to 2022
$961k
Leonard Davis Institute (LDI) Center for Health Incentives and Behavioral Economics (CHIBE) Pilot Grant at the University of PennsylvaniaNIDDK NIH HHS #1K23DK115897-01NIDDK NIH HHS K23 DK115897Translational Medicine and Therapeutics (ITMAT)
6 · The paper itself

Abstract

Kidney transplant recipients (KTRs) and liver transplant recipients (LTRs) have significant post-transplant weight gain and low physical activity. We conducted a home-based, remotely monitored intervention using wearable accelerometer devices to promote post-transplant physical activity. We randomized 61 KTRs and 66 LTRs within 24 months of transplant to: (i) control, (ii) accelerometer or (iii) intervention: accelerometer paired with financial incentives and health engagement questions to increase steps by 15% from baseline every 2 weeks. The primary outcome was weight change. A co-primary outcome for the two accelerometer arms was steps. Participants were recruited at a median of 9.5 [3-17] months post-transplant. At 3 months, there were no significant differences in weight change across the three arms. The intervention arm was more likely to achieve ≥7000 steps compared to control with device (OR 1.99, 95% CI: 1.03-3.87); effect remained significant after adjusting for demographics, allograft, time from transplant and baseline weight. Adherence to target step goals was 74% in the intervention arm, 84% of health engagement questions were answered correctly. A pilot study with financial incentives and health engagement questions was feasible and led KTRs and LTRs to walk more, but did not affect weight. A definitive trial is warranted.

Indexed as

Organ TransplantationWalkingExerciseHumansMotivationPilot Projectsbehavioral economicsbehavior changeexercisephysical activityremote monitoringself-care

Identifiers

PMID31925833
PMCPMC7239718
OpenAlexW2999553876

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.