Evidence map›Paper›PMID 31925789›Full record

ArticleAllergy2020

Postbronchodilator lung function improvements with benralizumab for patients with severe asthma.

Sameer K Mathur, Brian D Modena, Hanneke Coumou, Peter Barker, James L Kreindler, James G Zangrilli

Abstract readLetter
In one paragraph

Article in Allergy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Anti-IL-5 therapies for asthma.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Trial
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sameer K MathurDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.ORCID 0000-0001-7656-0256
Brian D ModenaDepartment of Medicine, National Jewish Health, Denver, CO, USA.ORCID 0000-0002-4406-8336
Hanneke CoumouDepartment of Pulmonary Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Peter BarkerResearch and Development, AstraZeneca, Gaithersburg, MD, USA.
James L KreindlerRespiratory Biologics, AstraZeneca, Wilmington, DE, USA.
James G ZangrilliGlobal Medical Affairs, AstraZeneca, Gaithersburg, MD, USA.

Funding

Genomic Analysis of Epithelial Growth and Repair Mechanisms in Aspirin Exacerbated Respiratory DiseaseK23HL144418 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI MODENA, BRIAN DAVID · 2018 to 2021
$502k
NHLBI NIH HHS K23 HL144418
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Asthmatic AgentsAsthmaAntibodies, Monoclonal, HumanizedHumansLungAnti-Asthmatic AgentsAntibodies, Monoclonal, Humanizedbenralizumab

Identifiers

PMID31925789
PMCPMC7317975

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.