Evidence map›Paper›PMID 31925642›Full record

Observational studyInternational urology and nephrology2020

Kidney transplantation improves arterial stiffness in patients with end-stage renal disease.

Sujuan Feng, Haozhou Wang, Jing Yang, Xiaopeng Hu, Wei Wang, Hang Liu, Han Li, Xiaodong Zhang

Abstract readComparative StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in International urology and nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sujuan FengInstitute of Uro-Nephrology, Beijing Chao-Yang Hospital, Capital Medical University, #8 Gong Ti Nan Lu, Beijing Chao yang District, Beijing, 100020, China.
Haozhou WangInstitute of Uro-Nephrology, Beijing Chao-Yang Hospital, Capital Medical University, #8 Gong Ti Nan Lu, Beijing Chao yang District, Beijing, 100020, China.
Jing YangInstitute of Uro-Nephrology, Beijing Chao-Yang Hospital, Capital Medical University, #8 Gong Ti Nan Lu, Beijing Chao yang District, Beijing, 100020, China.
Xiaopeng HuInstitute of Uro-Nephrology, Beijing Chao-Yang Hospital, Capital Medical University, #8 Gong Ti Nan Lu, Beijing Chao yang District, Beijing, 100020, China.
Wei WangInstitute of Uro-Nephrology, Beijing Chao-Yang Hospital, Capital Medical University, #8 Gong Ti Nan Lu, Beijing Chao yang District, Beijing, 100020, China.
Hang LiuInstitute of Uro-Nephrology, Beijing Chao-Yang Hospital, Capital Medical University, #8 Gong Ti Nan Lu, Beijing Chao yang District, Beijing, 100020, China.
Han LiInstitute of Uro-Nephrology, Department of Blood Purification, Beijing Chao-Yang Hospital, Capital Medical University, #8 Gong Ti Nan Lu, Beijing Chao yang District, Beijing, 100020, China. lihanccmu1@163.com.
Xiaodong ZhangInstitute of Uro-Nephrology, Beijing Chao-Yang Hospital, Capital Medical University, #8 Gong Ti Nan Lu, Beijing Chao yang District, Beijing, 100020, China. zhangxiaodmail@sina.com.
Capital Medical University · CNBeijing Chao-Yang Hospital · CN

Funding

ZYLX201408 ZYLX201408
6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) is the leading cause of mortality among the patients with end-stage renal disease (ESRD). Arterial stiffness is a well-accepted predictor of cardiovascular mortality in general population and ESRD patients. The aim of this study was to compare the change of arterial stiffness in kidney transplant recipients (KTRs) and ESRD patients, and further investigate the impact of kidney transplantation (KT) on arterial stiffness.

methodsA total of 138 maintenance hemodialysis patients, 198 KTRs and 75 healthy volunteers were enrolled in this study. The carotid-femoral pulse wave velocity (CF-PWV) and carotid-radial PWV (CR-PWV) were determined, and the correlations of PWV with biochemical parameters were analyzed.

resultsCF-PWV was highest in the maintenance hemodialysis patients, but similar between KTRs and healthy volunteers. Bivariate correlation analysis among KTRs demonstrated that CF-PWV was positively correlated with high level of peripheral diastolic blood pressure, pulse pressure, mean artery pressure, BUN and HDL, but negatively correlated with albumin. Univariate polytomous logistic regression analysis showed that age, BMI, systolic blood pressure, pulse pressure, length of KT and BUN were associated with the increase of CF-PWV value.

conclusionsAortic stiffness could be improved after KT. Meanwhile, age, BMI, systolic blood pressure, pulse pressure, length of KT and BUN were independent predictors of the increase of CF-PWV in KTRs.

Indexed as

Kidney TransplantationVascular StiffnessAdultCross-Sectional StudiesFemaleHumansKidney Failure, ChronicMaleMiddle AgedRenal DialysisAortic stiffnessCardiovascular diseaseKidney transplantationPulse wave velocity

Identifiers

PMID31925642
OpenAlexW2999870038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.