Evidence map›Paper›PMID 31925607›Full record

ArticleAIDS and behavior2020

Sexual Behavior and Perceived HIV Risk Among HIV-Negative Members of Serodiscordant Couples in East Africa.

Valentine Wanga, Jared M Baeten, Elizabeth A Bukusi, Nelly R Mugo, Stephen Asiimwe, Kenneth Ngure, Andrew Mujugira, Timothy Muwonge, Josephine B Odoyo, Jessica E Haberer and 3 more

Open access · greenAbstract read
In one paragraph

Article in AIDS and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Valentine WangaUniversity of Washington, 325 Ninth Ave Box 359927, Seattle, WA, 98104, USA.
Jared M BaetenUniversity of Washington, 325 Ninth Ave Box 359927, Seattle, WA, 98104, USA.
Elizabeth A BukusiUniversity of Washington, 325 Ninth Ave Box 359927, Seattle, WA, 98104, USA.
Nelly R MugoUniversity of Washington, 325 Ninth Ave Box 359927, Seattle, WA, 98104, USA.
Stephen AsiimweKabwohe Clinical Research Center (KCRC), Kabwohe, Uganda.
Kenneth NgureJomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya.
Andrew MujugiraInfectious Diseases Institute, Kampala, Uganda.
Timothy MuwongeInfectious Diseases Institute, Kampala, Uganda.
Josephine B OdoyoKenya Medical Research Institute, Nairobi, Kenya.
Jessica E HabererMassachusetts General Hospital, Boston, USA.
Connie CelumUniversity of Washington, 325 Ninth Ave Box 359927, Seattle, WA, 98104, USA.
Renee HeffronUniversity of Washington, 325 Ninth Ave Box 359927, Seattle, WA, 98104, USA. rheffron@uw.edu.ORCID http://orcid.org/0000-0001-6039-0352
Partners Demonstration Project Team
University of Washington · USJomo Kenyatta University of Agriculture and Technology · KEKenya Medical Research Institute · KEInfectious Diseases Institute · UG

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI CONNIE L CELUM · 1988 to 2026
$104.9M
Optimizing Antiretroviral-Based HIV Prevention for HIV Serodiscordant CouplesR01MH095507 · NIMH · UNIVERSITY OF WASHINGTON · PI BAETEN, JARED · 2011 to 2020
$6.1M
Bill and Melinda Gates Foundation OPP1056051NIAID NIH HHS P30 AI027757NIMH NIH HHS R01 MH095507NIMH NIH HHS R01MH095507USAID AID-OAA-A-12-00023
6 · The paper itself

Abstract

HIV risk perception may influence the use of HIV prevention interventions. Using data from HIV-negative adults enrolled in a study of pre-exposure prophylaxis (PrEP) and antiretroviral therapy for HIV-serodiscordant couples in Kenya and Uganda, we examined associations between: (1) condom use and risk perception and (2) risk perception and PrEP adherence. Two-thirds of HIV-negative partners reported condomless sex with their HIV-positive partner or another partner in the month prior to study enrollment. Compared to those who reported no condomless sex, participants who reported condomless sex during the month prior to study visit had fivefold higher odds of reporting "high risk" vs "no risk" perception (36.3 versus 10.9%: aOR 4.9, 95% CI 3.4-6.9). Reporting condomless sex in the most recent sex act was associated with increased odds of perceiving some HIV risk (aOR for high risk = 7.3, 95% CI 4.9-10.8; aOR for moderate risk = 4.8, 95% CI 3.5-6.7; aOR for low risk = 3.5, 95% CI 2.7-4.6). We found no significant association between risk perception and PrEP adherence. Sexual behavior aligned with perceived HIV risk, which can facilitate an HIV-negative individual's decisions about PrEP use.

Indexed as

Pre-Exposure ProphylaxisAdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCondomsFemaleHIV InfectionsHIV SeronegativityHIV SeropositivityHumansKenyaMaleMiddle AgedRisk FactorsRisk-TakingSexual BehaviorAnti-HIV AgentsCondomless sexHIVPrEPRisk perceptionSerodiscordant

Identifiers

PMID31925607
PMCPMC7319874
OpenAlexW2998855991

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.